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  1. Optimal positioning of hematopoietic stem cell transplantation for older patients with myelodysplastic syndromes

    ... varies with MDS risk. For those with low/intermediate-1 International Prognostic Scoring System (IPSS) risk, non-HSCT treatments may be ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update

    ... been shown to be active in numerous studies including International Prognostic Scoring System (IPSS) intermediate-1 to high risk patients, in ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Combination strategies in myelodysplastic syndromes.

    ... as higher risk and lower risk on the basis of the International Prognostic Scoring System . Currently, lenalidomide , azacitidine ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Durable long-term responses in patients with myelodysplastic syndromes treated with lenalidomide.

    ... yet been reported. Here, we describe 6 patients with International Prognostic Scoring System low- or intermediate-1-risk MDS who began ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Practical use of azacitidine in higher-risk myelodysplastic syndromes: an expert panel opinion.

    ... over conventional care regimens in patients with International Prognostic Scoring System (IPSS) intermediate-2 (Int-2) and high-risk ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes.

    ... with conventional care regimens in patients with International Prognostic Scoring System -defined intermediate-2- or high-risk myelodysplastic ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis

    ... of p73 methylation was significantly correlated with the International Prognostic Scoring System subgroup ( r  =  0.904, p  <  0.001). ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Perceptions of Disease State, Treatment Outcomes, and Prognosis Among Patients with Myelodysplastic Syndromes: Results From an Internet-Based Survey.

    ... was 6 years. Many patients (55%) did not know their International Prognostic Scoring System score, 42% were unaware of their blast ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy

    ... (88%) had higher risk disease according to the Revised International Prognostic Scoring System . Median overall survival for this group of 39 ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Azacitidine for treatment of patients with myelodysplastic syndromes (MDS): practical recommendations of the German MDS Study Group.

    ... to conventional care regimens for patients with International Prognostic Scoring System score of intermediate-2 or high-risk MDS. This review aims ...

    Research Article last updated 07/20/2018 - 5:14pm.