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  1. Comparable outcomes between younger (⩽40 years) and older (>40 years) adult patients with severe aplastic anemia after HLA-matched sibling stem cell transplantation using fludarabine-based conditioning

    ... Allogeneic stem cell transplantation from HLA -matched siblings (MSD-SCT) for elderly patients with severe ...

    Research Article last updated 11/28/2016 - 9:28am.

  2. Bone marrow transplantation versus immunosuppressive therapy in patients with acquired severe aplastic anemia

    ... bone marrow transplantation (BMT), usually from an HLA identical sibling. Whereas long-term survival is comparable with either ... survival (FFS), in patients receiving first-line BMT from an HLA identical sibling, or the first-line IST. Young patients with low ...

    Research Article last updated 07/18/2016 - 10:11am.

  3. Analysis of allogeneic hematopoietic stem cell transplantation with high-dose cyclophosphamide-induced immune tolerance for severe aplastic anemia

    ... the Beijing Military Region General Hospital. All were HLA mismatched and received CSA; 11 received ATG-intensive immune therapy. ...

    Research Article last updated 11/01/2016 - 1:59pm.

  4. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for ...

    Research Article last updated 11/01/2016 - 1:55pm.

  5. Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC (ExpMACs)

    ... is to expand access for patients who lack a fully HLA ( Human leukocyte antigen ) matched sibling donor and who are ... Patients who lack a fully HLA matched sibling and who are candidates for allogeneic hematopoietic ...

    Clinical Trial last updated 06/13/2016 - 1:47pm.

  6. Alternative donor transplants for severe aplastic anemia: current experience

    ... (SAA), who lack a human leukocyte antigen ( HLA ) identical sibling donor (SIB), have two therapeutic options: ... or a family mismatched member, in most instances genetically HLA haplo-mismatched (HAPLO). In the present review, we will discuss recent ...

    Research Article last updated 06/07/2016 - 10:52am.

  7. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for ...

    Research Article last updated 10/06/2016 - 9:48am.

  8. Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GvHD?

    ... anemia (SAA) underwent marrow transplantation from HLA -identical siblings following a standard conditioning regimen with ...

    Research Article last updated 09/13/2016 - 12:50pm.

  9. A Comparison of Outcomes for Cord Blood Transplant and Unrelated Bone Marrow Transplant in Adult Aplastic Anemia

    ... To identify differences in outcomes of UCBT and HLA -matched or mismatched unrelated bone marrow transplantation ...

    Research Article last updated 08/15/2016 - 1:06pm.

  10. Biomarkers for predicting clinical response to immunosuppressive therapy in aplastic anemia

    ... the availability of a human leukocyte antigen ( HLA )-matched donor. Although IST is a promising treatment option, the ... choice for AA patients, including up-front HSCT from HLA-matched unrelated donor . The present review summarizes studies ...

    Research Article last updated 06/22/2016 - 10:19am.