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  1. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... mortality (TRM) and availability of a suitable HLA -matched donor. Results from several large centres indicated 3-year ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.

    ... chemotherapy, the impact of the availability of an HLA -identical sibling donor on an intention-to treat basis. Additionally, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: long-term results of a retrospective study on behalf of the Gruppo Italiano Trapianto Midollo Osseo (GITMO).

    ... to 60 years (median 32 years). Twenty-three donors were HLA -identical (22 siblings and one unrelated) and 3 were HLA-mismatched (2 related and one unrelated). RESULTS: Fifteen ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Improved outcome of patients older than 30 years receiving HLA-identical sibling hematopoietic stem cell transplantation for severe acquired aplastic anemia using fludarabine-based conditioning: a comparison with conventional conditioning regimen.

    ... Older age is a limitation for HLA -identical sibling hematopoietic stem cell transplantation (HSCT) as ... impact of age in older patients with SAA receiving an HLA-identical sibling HSCT. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Aplastic anemia: first-line treatment by immunosuppression and sibling marrow transplantation.

    ... A for patients without a sibling donor and HLA identical sibling transplant for patients younger than age 40 with a ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Successful bone marrow transplantation for children with aplastic anemia based on a best-available evidence strategy.

    ... had ATG + CY + Flu, and five had ATG + CY. Donors were HLA -matched siblings in 10, HLA-mismatched family in one, HLA-matched unrelated in three, and ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.

    ... of these cells is a first-line treatment option if HLA -matched related donors are available. First-line immunosuppressive ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Comparison of Outcomes after Transplantation of G-CSF-Stimulated Bone Marrow Grafts versus Bone Marrow or Peripheral Blood Grafts from HLA-Matched Sibling Donors for Patients with Severe Aplastic Anemia.

    ... blood progenitor cells (PBPC) (n = 134) from an HLA -matched sibling. Transplantations occurred in 1997 to 2003. Rates of ... for SAA. Taken together, BM is the preferred graft for HLA-matched sibling transplants for SAA. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Aplastic anemia: pathophysiology and treatment.

    ... transplantation (HSCT) for acquired AA, whether from an HLA identical sibling or an unrelated donor , provides an excellent ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Impact of age on outcomes after bone marrow transplantation for acquired aplastic anemia using HLA-matched sibling donors.

    ... BACKGROUND: Transplantation from an HLA -matched sibling is the treatment of choice for young patients with ... in 1307 patients with severe aplastic anemia after HLA-matched sibling transplantation using logistic and Cox regression ...

    Research Article last updated 07/20/2018 - 5:14pm.