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  1. Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR

    ... stem cell transplantation from a related or unrelated HLA matched donor. The effect of 5-azacytidine on global gene ...

    Clinical Trial last updated 05/02/2016 - 11:10am.

  2. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... Patients with hematologic malignancy must have no HLA identical sibling or suitable unrelated donor OR time needed to ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  3. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... severe sickle cell disease (SCD) and B-thalassemia from HLA -matched family donors has excellent results thus far. Our long term ... approach in the patients with SCD and B-thalassemia with HLA-matched family donors, but using an increased intensity regimen in a subset ...

    Clinical Trial last updated 04/28/2016 - 9:09am.

  4. Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia

    ... and antithymocyte globulin followed by HLA -genotypically identical sibling donor hematopoietic stem cell ...

    Clinical Trial last updated 04/28/2016 - 8:53am.

  5. Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

    ... Patients are stratified according to donor/recipient HLA type (identical vs other). Cytoreductive combination ...

    Clinical Trial last updated 04/28/2016 - 8:49am.

  6. Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis

    ... for patients with human leukocyte antigen ( HLA ) matched unrelated (MUD) and mismatched unrelated (MMUD) donors. Other ...

    Clinical Trial last updated 04/27/2016 - 9:38am.

  7. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... (HCT) from human leukocyte antigen ( HLA )-haploidentical related donors for patients with nonmalignant inherited disorders who do not have an HLA-matched related or unrelated donor . SECONDARY OBJECTIVES: ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.

  8. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... using an human leukocyte antigen ( HLA ) matched sibling donor, only about 25% of patients have such a donor. ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  9. Bone Marrow Transplant

    ... a suitable match with the patient's type. This is called HLA matching. A well-matched donor is important to the success of the ...

    Topic section last updated 03/29/2016 - 7:27pm.

  10. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... there should be no readily available consenting HLA - matched related donor who is either matched fully matched or mismatched at only one locus of HLA-A, -B, and DRB1. No availability of a readily available HLA-matched ...

    Clinical Trial last updated 06/06/2016 - 3:37pm.