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  1. IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution.

    ... identified in 4.6% of 477 patients with MDS based on the FAB classification and in 2.2 % of 368 patients based on the 2008 WHO ... lower-risk MDS, based on international prognosis scoring system (IPSS), FAB classification, WHO classification, or revised IPSS (all ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Improved risk stratification by the integration of the revised International Prognostic Scoring System with the Myelodysplastic Syndromes Comorbidity Index

    ... analysed 363 patients diagnosed with MDS according to the FAB criteria between 2000 and 2012. The IPSS, MD Anderson Risk Model Score (MDAS), World Health Organisation (WHO)-classification based Prognostic Scoring System (WPSS), refined WPSS (WPSS-R), ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Overview of myelodysplastic syndromes

    ... entity in hematology in 1982 by the French-American-British (FAB) group. Although widely accepted, this classification was revised in 2001 and again in 2008 by the World Health ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Types

    ... History of Classification Before 1976, the term "MDS" ... This system is called the French-American-British or FAB system. It is based on how blood and bone marrow cells look. ...

    Topic section last updated 07/20/2018 - 5:15pm.

  5. MEDALIST Trial

    ... to World Health Organization (WHO)/French American British (FAB) classification that meets IPSS R classification of very low, low, or ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  6. What is My Doctor thinking?: MDS Classification, IPSS and IPSS-R Scoring Systems for MDS

    ... International Prognostic Scoring System (IPSS) is a classification tool used by doctors to help them classify your MDS and your ... the previous classification models such as the WHO and FAB models that have helped evolve the understanding of MDS through the IPSS ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  7. What is My Doctor thinking?: MDS Classification, IPSS and IPSS-R Scoring Systems for MDS

    ... The International Prognostic Scoring System (IPSS) is a classification tool used by doctors to help them classify your MDS and your ... the previous classification models such as the WHO and FAB models that have helped evolve the understanding of MDS through the IPSS ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  8. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... marrow ), with French-American-British Cooperative group (FAB) classification other than M3 (acute promyelocytic leukemia), documented by ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  9. Myelodysplastic Syndromes are a collection of diseases with common, but also different characteristics

    ... diagnostic criteria; there is the French-American-British (FAB) and the World Health Organization (WHO) classification.  These classification systems describe the cellular nature and ... is provided by the International Prognostic Scoring System (IPSS).  The newest version of IPSS classifies people in 5 ...

    Research Review last updated 05/02/2016 - 9:22am.

  10. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... leukemia at diagnosis; Any unfavorable sub type by FAB or WHO classification; High-risk cytogenetics (eg those associated with ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.