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Research Articles

Compiled for your convenience are articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology.

Article Title Original Publication Date Journal Bone Marrow Disease
Patients with paroxysmal nocturnal hemoglobinuria demonstrate a prothrombotic clotting phenotype which is improved by complement inhibition with eculizumab Aug 2020 American Journal of Hematology Paroxysmal Nocturnal Hemoglobinuria (PNH)
Clinical decision-making and treatment of myelodysplastic syndromes Dec 2023 American Journal of Hematology Myelodysplastic Syndromes (MDS)
Massive hemolysis in paroxysmal nocturnal hemoglobinuria after switching from proximal complement inhibitor to anti-C5 therapy: A lesson not to be forgotten Oct 2024 American Journal of Hematology Paroxysmal Nocturnal Hemoglobinuria (PNH)
Complement inhibition in medicine: Hematology and beyond; complement inhibition in hematology: PNH and beyond May 2023 American Journal of Hematology Paroxysmal Nocturnal Hemoglobinuria (PNH)
Myelodysplastic syndromes with ring sideroblasts (MDS-RS) and MDS/myeloproliferative neoplasm with RS and thrombocytosis (MDS/MPN-RS-T) - "2021 update on diagnosis, risk-stratification, and management" Mar 2021 American Journal of Hematology Myelodysplastic Syndromes (MDS)
How I Diagnose Low-Grade Myelodysplastic Syndromes May 2020 American Journal of clinical Pathology Myelodysplastic Syndromes (MDS)
Calculator-free point-of-care prognostication in myelodysplastic syndromes. Jan 2019 Am J Hematol Myelodysplastic Syndromes (MDS)
Effectiveness of eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) with or without aplastic anemia in the International PNH Registry Jan 2019 Am J Hematol Aplastic Anemia, Paroxysmal Nocturnal Hemoglobinuria (PNH)
HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML Jul 2020 Aging Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
Complement Inhibition in Paroxysmal Nocturnal Hemoglobinuria (PNH): A Systematic Review and Expert Opinion from Central Europe on Special Patient Populations Jun 2023 Advances in Therapy Paroxysmal Nocturnal Hemoglobinuria (PNH)