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Research Articles

Compiled for your convenience are articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology.

Article Title Original Publication Date Journal Bone Marrow Disease
The Genomics of Myelodysplastic Syndromes: Origins of Disease Evolution, Biological Pathways, and Prognostic Implications Nov 2020 Cells Myelodysplastic Syndromes (MDS)
Danicopan: an oral complement factor D inhibitor for paroxysmal nocturnal hemoglobinuria Oct 2020 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study Oct 2020 Journal of clinical oncology: official journal of the American Society Clinical Oncology Myelodysplastic Syndromes (MDS)
One-year efficacy and safety of ravulizumab in adults with paroxysmal nocturnal hemoglobinuria naïve to complement inhibitor therapy: open-label extension of a randomized study Oct 2020 Therapeutic Advances in Hematology Paroxysmal Nocturnal Hemoglobinuria (PNH)
Silver lining: reduced relapse with chronic GVHD after transplant for MDS Oct 2020 Clinical Cancer Research: an official Journal of the American Association of Cancer Research Graft Versus Host Disease (GVHD), Myelodysplastic Syndromes (MDS)
Phase II study of the clinical efficacy and safety of tosedostat in patients with myelodysplastic syndromes (MDS) after failure of hypomethylating agent-based therapy Oct 2020 Leukemia & Lymphoma Myelodysplastic Syndromes (MDS)
Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes Oct 2020 Annals of internal medicine Myelodysplastic Syndromes (MDS)
Following in the footsteps of acute myeloid leukemia: are we witnessing the start of a therapeutic revolution for higher-risk myelodysplastic syndromes? Oct 2020 Leukemia & Lymphoma Myelodysplastic Syndromes (MDS)
Haploidentical hematopoietic stem cell transplantation in aplastic anemia: a systematic review and meta-analysis of clinical outcome on behalf of the severe aplastic anemia working party of the European group for blood and marrow transplantation (SAAWP of Oct 2020 Bone Marrow Transplantation Aplastic Anemia
Following in the footsteps of acute myeloid leukemia: are we witnessing the start of a therapeutic revolution for higher-risk myelodysplastic syndromes? Oct 2020 Leukemia & Lymphoma Myelodysplastic Syndromes (MDS)