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Research Articles

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Compiled for your convenience are articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology.

Article Title Original Publication Date Journal Bone Marrow Disease
Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria. Mar 2019 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Conditional survival and standardized mortality ratios of patients with severe aplastic anemia surviving at least one year after hematopoietic cell transplantation or immunosuppressive therapy Jun 2023 Haematologica Aplastic Anemia
To Target the Untargetable: Elucidation of Synergy of APR-246 and Azacitidine in TP53 Mutant Myelodysplastic Syndromes and Acute Myeloid Leukemia Jun 2020 Haematologica Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study Apr 2019 Haematologica Aplastic Anemia
Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria Jan 2020 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Time without transfusion reliance: a novel patient-centric metric for new therapies in myelodysplastic syndromes Apr 2023 Haematologica Myelodysplastic Syndromes (MDS)
Phase II trials of zilucoplan in paroxysmal nocturnal hemoglobinuria Aug 2023 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Current use of androgens in bone marrow failure disorders: a report from the Severe Aplastic Anemia Working Party of the European Society of Blood and Marrow Transplantation May 2023 Haematologica Aplastic Anemia
Antithymocyte globulin and cyclosporin: standard of care also for older patients with aplastic anemia. Feb 2019 Haematologica Aplastic Anemia
Danicopan: an oral complement factor D inhibitor for paroxysmal nocturnal hemoglobinuria Oct 2020 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)