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  1. Supportive Care

    ... is not a cure. This approach includes the use of: Blood transfusions Iron chelation therapy to treat iron ... similar EPO, and comes in the brand name Aranesp®. White blood cell growth factors are sometimes used. These include G-CSF ( ...

    Page last updated 08/29/2013 - 4:20pm.

  2. Chronic Myeloproliferative Neoplasms (MPN)

    ... bone marrow makes too many of one or more types of blood cells. Neoplasms usually get worse over time as the number of extra blood ... Chronic myelogenous leukemia (CML), the overproduction of white cells (granulocytes) and other cells Polycythemia vera, the ...

    Topic section last updated 07/07/2016 - 3:19pm.

  3. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... and radiation at reduced doses followed by a cord blood transplant are at treating cancer. The stem cells chosen for the ... or myeloproliferative disorder; Therapy related AML; White cell count at presentation > 100,000; Presence of extramedullary ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  4. Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

    ... phase II trial studies how well donor umbilical cord blood transplant with or without ex-vivo expanded cord blood progenitor ... bone marrow make stem cells, red blood cells, white blood cells, and platelets. It is not yet known whether giving donor ...

    Clinical Trial last updated 04/27/2016 - 1:17pm.

  5. Matthew J. Walter, MD

    ... a mutation in one of these genes (U2AF1) affects blood cell formation in mice and alters the splicing of RNA in bone marrow ... that mice expressing the mutant U2AF1 gene have low white blood cell counts, similar to that seen in MDS patients. Mutant mouse ...

    Grant Recipient last updated 08/18/2014 - 10:07am.

  6. Overlap Syndromes: When PNH Appears with Aplastic Anemia or MDS

    ... (scarring in the marrow), a chronically high white blood cell or platelet count, especially if they have the JAK2 ...

    Interview last updated 05/14/2015 - 1:53pm.

  7. BMT - Bone Marrow v Stem Cell

    ... bone marrow from a donor. This was put into the patient’s blood stream where it would find its way to the bone marrow and started to ... blood stem cells (PBSC) – The donor is given a white cell  growth factor  that increases the production of white blood ...

    Topic section last updated 02/23/2016 - 12:59pm.

  8. Transplantation


    Page last updated 01/20/2015 - 4:45pm.

  9. Iron Chelation Therapy

    ... This can be a problem for people who get lots of red blood cell transfusions. Red blood cells contain iron. Each time you get a ... well tolerated by patients, but it can cause a drop in white blood cell counts, so patients need to have their blood checked ...

    Page last updated 01/20/2015 - 4:40pm.

  10. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... recover faster following a stem cell transplant . Blood stem cells are very young blood cells that grow in the body to become red or white blood cells or platelets. The transplant uses stem cells in the blood ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.