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  1. MDS and Inflammation

    ... cellular effectors of inflammatory responses involve white blood cells, immune cells, blood vessels and additional molecular factors. This ...

    Interview last updated 02/14/2017 - 8:52am.

  2. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... up to 24 hours before initiating treatment and to control blood counts during the first cycle of chemotherapy after azacitidine ... counts; however, at the time of treatment initiation, white blood cell (WBC) should be < 30,000/uL (can be controlled with ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  3. Matthew J. Walter, MD

    ... a mutation in one of these genes (U2AF1) affects blood cell formation in mice and alters the splicing of RNA in bone marrow ... that mice expressing the mutant U2AF1 gene have low white blood cell counts, similar to that seen in MDS patients. Mutant mouse ...

    Grant Recipient last updated 08/18/2014 - 10:07am.

  4. David Araten, MD

    ... by itself provide a very large percentage of the patient's blood cells. This clone has as its feature the presence of a mutation ... estimated from the platelet count and the percentage of PNH white cells. In the past there have been tests to identify platelets with the ...

    Grant Recipient last updated 11/30/2016 - 10:51am.

  5. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... to what is described above. CD20 is a type of marker for white blood cells. White blood cells help protect the body from infections. NK ...

    Clinical Trial last updated 06/06/2016 - 10:28am.

  6. Iron Chelation Therapy

    ... This can be a problem for people who get lots of red blood cell transfusions. Red blood cells contain iron. Each time you get a ... well tolerated by patients, but it can cause a drop in white blood cell counts, so patients need to have their blood checked ...

    Page last updated 01/20/2015 - 4:40pm.

  7. Overlap Syndromes: When PNH Appears with Aplastic Anemia or MDS

    ... (scarring in the marrow), a chronically high white blood cell or platelet count, especially if they have the JAK2 ...

    Interview last updated 05/14/2015 - 1:53pm.

  8. Transplantation

     

    Page last updated 01/20/2015 - 4:45pm.

  9. Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

    ... phase II trial studies how well donor umbilical cord blood transplant with or without ex-vivo expanded cord blood progenitor ... bone marrow make stem cells, red blood cells, white blood cells, and platelets. It is not yet known whether giving donor ...

    Clinical Trial last updated 04/27/2016 - 1:17pm.

  10. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... and radiation at reduced doses followed by a cord blood transplant are at treating cancer. The stem cells chosen for the ... or myeloproliferative disorder; Therapy related AML; White cell count at presentation > 100,000; Presence of extramedullary ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.