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  1. SAA Patient Dominique Hughes Contributes to NIH Research

    ... 2015 I had a bone marrow transplant done from an unrelated donor .  But first, I had a genetic sequencing study done to see if there ...

    Patient Chronicle last updated 03/21/2017 - 11:32am.

  2. Allo HSCT Using RIC for Hematological Diseases

    ... (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion. The primary objective is to evaluate rates of ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  3. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... did not occur, with all patients achieving complete donor lymphohematopoietic chimerism. Unfortunately, recipients of G-CSF ... from an HLA identical sibling or match unrelated donor using the identical conditioning regimen utilized in ... HLA locus mismatched family donor or 10/10 matched unrelated donor at the allelic level (HLA alleles A, B, C, DR, and DQ). ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  4. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... This phase II trial studies how well donor peripheral blood stem cell (PBSC) transplant works in treating patients ... option to patients who do not have matched related or unrelated donors, especially for patients from ethnic minority groups. The ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  5. T-cell Depleted Alternative Donor Transplantation

    ... a stem cell transplant from an alternative (unrelated and mismatched related) donor. The secondary objectives include evaluation of engraftment , ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.

  6. Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

    ... how well umbilical cord blood transplant from a donor works in treating patients with hematological cancer. Giving ... stem cells . When the healthy stem cells from an unrelated donor , that do not exactly match the patient's blood, are infused ...

    Clinical Trial last updated 04/28/2016 - 1:52pm.

  7. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... disorders who do not have an HLA-matched related or unrelated donor . SECONDARY OBJECTIVES: I. Determine whether nonmyeloablative ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.

  8. T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts (MOHEL)

    ... Unfortunately, there is not a perfectly matched stem cell donor (like a sister or brother) and the subject's disease is considered ... In recipients of mismatched family member or matched unrelated donor stem cell transplants, there is a greater risk of GVHD so ...

    Clinical Trial last updated 04/28/2016 - 12:15pm.

  9. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... or ethnic background. Prior transfusions from selected donor (as this could have cause recipient alloimmunization against the donor) Women of childbearing potential who currently are pregnant (HCG+) or ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  10. Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

    ... designed to block participant's body's ability to reject the donor's stem cells . Researchers also want to learn if giving AP1903 ... -matched for HLA-A, -B, C and DR matched or, b. Matched Unrelated Donor (MUD), 8/8 HLA-matched for HLA A, B, C and DRB1 using ...

    Clinical Trial last updated 06/06/2016 - 12:41pm.