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  1. Unrelated Donor Stem Cell Transplantation

    ... bone marrow failure states who lack a suitable sibling donor to undergo allogeneic hematopoietic progenitor cell transplantation using cells from unrelated individuals or cord blood registries. ...

    Clinical Trial last updated 04/27/2016 - 3:18pm.

  2. Unrelated Donor Stem Cell Transplantation

    ... bone marrow failure states who lack a suitable sibling donor to undergo allogeneic hematopoietic progenitor cell transplantation using cells from unrelated individuals or cord blood registries. ...

    Clinical Trial last updated 04/28/2016 - 2:16pm.

  3. Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant

    ... radiation therapy. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving ... an available 5-6/6 HLA -A, B, DRB1 matched sibling donor Pregnancy or breastfeeding Evidence of human immunodeficiency ...

    Clinical Trial last updated 05/02/2016 - 2:13pm.

  4. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... with marked improvements in outcomes for unrelated donor transplants. When considering treatments for newly diagnosed aplastic ... impair their quality of life. Recently, the outcomes of unrelated donor transplantation have markedly improved. Previously, there was a ...

    Interview last updated 11/28/2016 - 2:58pm.

  5. First-in Human Clinical Transplant Trial for Severe Aplastic Anemia

    ... for patients who lack an HLA identical sibling or unrelated donors. This work that we began aimed at helping patients that did not have an HLA matched donor started about 12 years ago. This is when we tried to come up with a ...

    Interview last updated 10/04/2017 - 1:36pm.

  6. Allo HSCT Using RIC for Hematological Diseases

    ... (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion. The primary objective is to evaluate rates of ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  7. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... did not occur, with all patients achieving complete donor lymphohematopoietic chimerism. Unfortunately, recipients of G-CSF ... from an HLA identical sibling or match unrelated donor using the identical conditioning regimen utilized in ... HLA locus mismatched family donor or 10/10 matched unrelated donor at the allelic level (HLA alleles A, B, C, DR, and DQ). ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  8. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... This phase II trial studies how well donor peripheral blood stem cell (PBSC) transplant works in treating patients ... option to patients who do not have matched related or unrelated donors, especially for patients from ethnic minority groups. The ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  9. Bone Marrow and Stem Cell Transplantation

    ... stem cell transplant , you should start looking for a donor now. It can take a long time to find a matched donor. This section ... donor . And it can take a long time to find a matched unrelated donor if no related donor is available. How does the search ...

    Page last updated 09/30/2014 - 11:47am.

  10. T-cell Depleted Alternative Donor Transplantation

    ... a stem cell transplant from an alternative (unrelated and mismatched related) donor. The secondary objectives include evaluation of engraftment , ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.