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  1. Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    ... patients with hematologic malignancies undergoing unrelated donor peripheral blood stem cell transplant . Giving chemotherapy and total-body irradiation before a donor peripheral blood stem cell transplant (PBSCT) helps stop the growth of ...

    Clinical Trial last updated 04/28/2016 - 1:49pm.

  2. Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantation

    ... the effect on grade II-IV GvHD when given after matched unrelated donor transplant (MUD). ...

    Clinical Trial last updated 05/02/2016 - 2:07pm.

  3. Bone Marrow Transplantation for Acquired Severe Aplastic Anemia

    ... ongoing progress in the use of SAA in the setting of unrelated donor transplants, which now provide outcomes similar, though still not ...

    Research Article last updated 01/20/2015 - 2:47pm.

  4. The diagnosis and treatment of aplastic anemia: a review

    ... therapy for patients <40 years when a matched sibling donor (MSD) is not available for transplant. MSD hematopoietic stem cell ... but a response rate of about 60 %. Front-line matched unrelated donor (MUD) appears to be a viable option in children with ...

    Research Article last updated 05/26/2015 - 10:30am.

  5. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... transplantation (SCT), stem cells are taken from a donor and given to a recipient. Sometimes the recipient s immune system ... improves the results of allogeneic SCT from HLA-matched unrelated donors. Objective: - To see if high doses of palifermin ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  6. Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association (AIEOP)

    ... stem cell transplant (HSCT) from a matched sibling donor (MSD) is the treatment of choice. If a MSD is not available, the options include immunosuppressive therapy (IST) or unrelated donor HSCT. The objective of this guideline is to provide ...

    Research Article last updated 05/27/2015 - 1:21pm.

  7. Hematopoietic stem cell transplantation for aplastic anemia and paroxysmal nocturnal hemoglobinuria: current evidence and recommendations

    ... is the preferred option for young AA patients with a sibling donor, whereas in older patients or in those to be grafted from an unrelated donor BMT is exploited as second-line treatment. Current results of ...

    Research Article last updated 11/03/2014 - 10:22am.

  8. Allogeneic haematopoietic stem cell transplantation in myelodysplastic syndromes

    ... human leukocyte antigen -identical sibling or match unrelated donor options. A preemptive management approach to patients at high risk ...

    Research Article last updated 09/24/2014 - 10:46am.

  9. Aplastic anemia: therapeutic updates in immunosuppression and transplantation

    ... in the matched setting, but with greater rates observed with unrelated and umbilical cord donors. The correlation of increasing age with the ... in adults with SAA. Outcomes with matched unrelated donor HSCT have improved, likely due to better donor selection, ...

    Research Article last updated 01/02/2013 - 2:25pm.

  10. Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

    ... leukocyte antigen ( HLA ) matched related donor (MRD) and matched unrelated donors (MUD) produces similar survival for patients with acute ...

    Research Article last updated 08/06/2013 - 2:12pm.