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  1. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... of progress in optimization of the conditioning regimens, donor hematopoietic cell source, and supportive care . Here, we review ... BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for patients who have ...

    Research Article last updated 10/06/2016 - 9:48am.

  2. Alternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1

    ... With increasing alternative donors available, the preferred donor or stem cell source is debated. We set out to study outcome in recipients ... donors, including 10/10 (n = 1959) or 9/10 matched unrelated donors (MUDs, n = 549), umbilical cord blood (UCB) grafts (n = 333), ...

    Research Article last updated 03/09/2017 - 8:22am.

  3. Shares her 11-year-old daughter's story

    ... anemia . Instead of immediately looking for a matched donor for a transplant, Brianna was immediately put on horse ATG and ... us and we weren’t quite ready to go with a matched unrelated donor . One was found, but it was a much older person at the upper ...

    Patient Chronicle last updated 01/04/2017 - 11:09am.

  4. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... patients with acquired SAA incorporating alternative donor sources, including cord blood. Average risk for non- engraftment ... included MRD BM (6/6 [n = 9], 5/6 [n = 2]) and unrelated CB (5/6 [n = 4], 4/6 [n = 2]). Five year OS was 67.6% ...

    Research Article last updated 04/09/2014 - 9:11am.

  5. The prognostic value of serum c-reactive protein, ferritin, and albumin prior to allogeneic transplantation for acute myeloid leukemia and myelodysplastic syndromes

    ... or myelodysplastic syndromes undergoing unrelated donor transplant reported to the Center for International Blood and Marrow ...

    Research Article last updated 10/06/2016 - 11:27am.

  6. Allogeneic transplantation for aplastic anemia

    ... severe aplastic anemia, HLA -matched sibling, unrelated donor , hematopoietic stem cell transplantation. RESULTS: Survival ...

    Research Article last updated 07/03/2012 - 2:57pm.

  7. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... disease severity (SAA vs. VSAA, p = 0.184), or according to donor type (MSD vs. UD, p = 0.699). Excellent outcomes of patients with VSAA ...

    Research Article last updated 05/14/2013 - 1:00pm.

  8. Recent developments in bone marrow transplants

    ... from an umbilical cord blood source or HLA–matched unrelated donor . Repeated infusions of mesenchymal stromal cells reduced the ...

    Article last updated 11/16/2016 - 2:56pm.

  9. Evolving hematopoietic stem cell transplantation strategies in severe aplastic anemia

    ... PURPOSE OF REVIEW: Significant improvements in unrelated donor hematopoietic stem cell transplantation (HSCT) in recent years have ...

    Research Article last updated 04/29/2016 - 10:19am.

  10. Overcoming age barrier to transplantation

    ... cells. Since a minority of patients have a matched sibling donor, success often depends on transplants from an unrelated adult donor or with umbilical cord blood. This has been made possible ...

    Article last updated 04/03/2017 - 2:00pm.