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  1. Alternative donor transplants for severe aplastic anemia: current experience

    ... human leukocyte antigen ( HLA ) identical sibling donor (SIB), have two therapeutic options: immunosuppressive therapy with ... of no response. The alternative donor source can be an unrelated donor (UD), a cord blood (CB) unit, or a family mismatched ...

    Research Article last updated 06/07/2016 - 10:52am.

  2. Alternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1

    ... With increasing alternative donors available, the preferred donor or stem cell source is debated. We set out to study outcome in recipients ... donors, including 10/10 (n = 1959) or 9/10 matched unrelated donors (MUDs, n = 549), umbilical cord blood (UCB) grafts (n = 333), ...

    Research Article last updated 03/09/2017 - 8:22am.

  3. Allogeneic BM transplantation for the treatment of aplastic anemia: current results and expanding donor possibilities

    ... BM transplantation from an HLA -identical sibling donor leads to long-term survival in the majority of patients (> 80%). ... a sibling donor, transplantation from a well-matched unrelated donor can be considered after failure of a previous course of ...

    Research Article last updated 01/07/2014 - 12:31pm.

  4. The prognostic value of serum C-reactive protein, ferritin, and albumin prior to allogeneic transplantation for acute myeloid leukemia and myelodysplastic syndromes

    ... or myelodysplastic syndromes undergoing unrelated donor transplant reported to the Center for International Blood and Marrow ...

    Research Article last updated 11/28/2016 - 9:44am.

  5. Shares her 11-year-old daughter's story

    ... anemia . Instead of immediately looking for a matched donor for a transplant, Brianna was immediately put on horse ATG and ... us and we weren’t quite ready to go with a matched unrelated donor . One was found, but it was a much older person at the upper ...

    Patient Chronicle last updated 01/04/2017 - 11:09am.

  6. Striking the right balance: optimizing conditioning regimens for unrelated donor bone marrow transplant for severe aplastic anemia.

    ...

    Research Article last updated 07/30/2012 - 1:14pm.

  7. Overcoming age barrier to transplantation

    ... cells. Since a minority of patients have a matched sibling donor, success often depends on transplants from an unrelated adult donor or with umbilical cord blood. This has been made possible ...

    Article last updated 04/03/2017 - 2:00pm.

  8. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... of progress in optimization of the conditioning regimens, donor hematopoietic cell source, and supportive care . Here, we review ... BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for patients who have ...

    Research Article last updated 11/01/2016 - 1:55pm.

  9. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... of progress in optimization of the conditioning regimens, donor hematopoietic cell source, and supportive care . Here, we review ... BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for patients who have ...

    Research Article last updated 10/06/2016 - 9:48am.

  10. Recent developments in bone marrow transplants

    ... from an umbilical cord blood source or HLA–matched unrelated donor . Repeated infusions of mesenchymal stromal cells reduced the ...

    Article last updated 11/16/2016 - 2:56pm.