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  1. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... patients with acquired SAA incorporating alternative donor sources, including cord blood. Average risk for non- engraftment ... included MRD BM (6/6 [n = 9], 5/6 [n = 2]) and unrelated CB (5/6 [n = 4], 4/6 [n = 2]). Five year OS was 67.6% ...

    Research Article last updated 04/09/2014 - 9:11am.

  2. Effect of stem cell source on outcomes after unrelated donor transplantation in severe aplastic anemia

    ... Outcome after unrelated donor bone marrow (BM) transplantation for severe aplastic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes - Lingering Uncertainties and Emerging Possibilities

    ... conditioning (RIC) regimens, increased availability of unrelated donors, new donor sources and improvements in transplant technology and supportive ...

    Research Article last updated 08/21/2014 - 9:28am.

  4. Bone Marrow and Stem Cell Transplantation

    ... stem cell transplant , you should start looking for a donor now. It can take a long time to find a matched donor. This section ... donor . And it can take a long time to find a matched unrelated donor if no related donor is available. How does the search ...

    Page last updated 09/30/2014 - 11:47am.

  5. Striking the right balance: optimizing conditioning regimens for unrelated donor bone marrow transplant for severe aplastic anemia.

    Journal Title:  Biol Blood Marrow Transplant Primary Author:  Ramos CA Author(s):  ...

    Research Article last updated 07/30/2012 - 1:14pm.

  6. Management of the refractory aplastic anemia patient: what are the options?

    ... refractory AA patients are fit and have a suitably matched donor, either a sibling (> 40-50 years) or unrelated donor . Patients lacking a fully matched donor should be ...

    Research Article last updated 01/07/2014 - 12:28pm.

  7. Interviews with the Experts Transplantation & GVHD: What Patients Need to Know

    ... umbilical cord blood, and peripheral blood of a suitable donor and are placed in a patient? That is a correct summation. Stem cells ... in patients who were randomized to receive stem cells (from unrelated donors) harvested either from bone marrow or from blood, showing  a ...

    Interview last updated 09/30/2014 - 11:07am.

  8. Blood stream infection after stem cell transplantation in children with idiopathic aplastic anemia

    ... therapy with anti-thymocyte globulin, transplantation from unrelated donors, frequent blood transfusion before transplantation, ... in patients who were transplanted from an unrelated donor , control of BSI is very important for success of HSCT in patients ...

    Research Article last updated 04/23/2014 - 10:34am.

  9. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... disease severity (SAA vs. VSAA, p = 0.184), or according to donor type (MSD vs. UD, p = 0.699). Excellent outcomes of patients with VSAA ...

    Research Article last updated 05/14/2013 - 1:00pm.

  10. Total Lymphoid Irradiation-Antithymocyte Globulin Conditioning and Allogeneic Transplantation for Patients with Myelodysplastic Syndromes and Myeloproliferative Neoplasms

    ... globulin (ATG) permits the establishment of donor hematopoiesis necessary for the graft-versus-malignancy effect ... between patients who received allografts from related or unrelated donors. The cumulative incidence of nonrelapse mortality (NRM) at ...

    Research Article last updated 04/17/2014 - 11:48am.