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  1. Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant

    ... as treosulfan and fludarabine phosphate, and TBI before a donor UCBT helps stop the growth of cancer cells and helps stop the patient's ... stem cells . When the stem cells from a related or unrelated donor , that do not exactly match the patient's blood, are infused ...

    Clinical Trial last updated 04/28/2016 - 12:13pm.

  2. Fludarabine/Clofarabine/Busulfan Combined With SAHA in Acute Leukemia

    ... must have a related, genotypically HLA identical donor, or they must have a unrelated donor who is 8/8 HLA match by high resolution typing. Patient ...

    Clinical Trial last updated 06/06/2016 - 11:07am.

  3. Busulfan and Cyclophosphamide Followed By ALLO BMT

    ... sources include: HLA -matched related or unrelated donor bone marrow (6/6 or 5/6 antigen match) HLA-matched related or ...

    Clinical Trial last updated 04/29/2016 - 1:23pm.

  4. Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia

    ... stem cell transplant using related or unrelated donor in persons 0-70 years of age diagnosed with dyskeratosis ... preparative regimens are included based on disease and donor type. Status:  ...

    Clinical Trial last updated 04/25/2016 - 10:59am.

  5. Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

    ... depleted stem cell graft from a related haploidentical donor. All patients are planned to receive two ATIR101 doses of 2×10E6 viable ... Availability of a fully matched related or unrelated donor following a donor search Diffusing capacity for carbon ...

    Clinical Trial last updated 04/29/2016 - 12:25pm.

  6. Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic

    ... progenitor cells from matched sibling and volunteer unrelated donors. Unfortunately, this process requires four to six days of ... Inclusion Criteria:   (DONOR): Age 18 to 70 years of age. ECOG performance status of 0 or 1. ...

    Clinical Trial last updated 04/29/2016 - 4:33pm.

  7. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... did not occur, with all patients achieving complete donor lymphohematopoietic chimerism. Unfortunately, recipients of G-CSF ... PBSC co-infused with a reduced dose of non-mobilized donor T-cells that have not undergone a TH-2 cytokine polarization. ... from an HLA identical sibling or match unrelated donor using the identical conditioning regimen utilized in ...

    Clinical Trial last updated 04/25/2016 - 10:08am.

  8. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... human leukocyte antigen ( HLA )-matched donor availability continues to be a major hurdle. Historically, HLA ... to allo-HCT using more traditional HLA matched related and unrelated donors. However, graft-versus-host disease (GvHD) continues ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  9. Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

    ... leukocyte antigen ( HLA )-identical related or unrelated donor cannot be identified within an appropriate time frame Karnofsky ...

    Clinical Trial last updated 04/29/2016 - 1:15pm.

  10. Telomere Length and Allogeneic Hematopoietic Cell Transplantation for Severe Aplastic Anemia

    ... treatment for those who lack a suitable matched related donor or are older. For young aplastic anemia patients, hematopoietic ... is recommended when a matched sibling donor is available. Unrelated HSCT (from a non-familial donor) does not achieve results that are as ...

    Research Review last updated 05/02/2016 - 9:13am.