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  1. Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome

    ... from either HLA -matched sibling or matched unrelated donor cures about 70 percent of patients with SAA and 30-60 percent of ...

    Clinical Trial last updated 04/25/2016 - 2:18pm.

  2. Bone Marrow Transplant

    ... cell transplants. A transplant may use cells taken from a donor or from the patient: Autologous transplants use a patient's ... donor. These might come from a sibling, or a matched unrelated donor (MUD). The donor's tissue type must be a suitable match ...

    Topic section last updated 03/29/2016 - 7:27pm.

  3. Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

    ... This phase II trial studies how well T cell depleted donor peripheral blood stem cell transplant works in preventing ... binding motif protein 45 [DRB1] molecularly matched) unrelated donor or related donor capable of donating PBSC DONOR: ...

    Clinical Trial last updated 06/13/2016 - 2:29pm.

  4. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... studies the safety of transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ ... must have no HLA identical sibling or suitable unrelated donor OR time needed to find an acceptable unrelated donor match ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  5. RIC Transplant Using Haplo Donors

    ... No available matched related or unrelated donor , OR a matched related or unrelated donor will not be available in ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  6. Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies

    ... malignancies who lack a suitably matched related or unrelated donor . The methodology will be one that has been successfully utilized in ...

    Clinical Trial last updated 04/29/2016 - 10:59am.

  7. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... physician immediately Research participants must have a donor or stem cell source identified for allogeneic transplantation, either related (7/8 or 8/8 allele matched or haploidentical), unrelated (7/8 or 8/8 allele match) donor, or cord blood stem cell source (at ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  8. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... myeloid leukemia, or chronic myelogenous leukemia undergoing donor peripheral blood stem cell transplant . Giving chemotherapy ... -matched (HLA-A, B, C, and DRB1 molecularly matched) unrelated donor or related donor capable of donating PBSC DONOR ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  9. Cord Blood Transplant

    ... Human Leukocyte Antigen ( HLA ) matched sibling donor is the most commonly used source of allogeneic stem cells . ... SCT. In the absence of an HLA matched sibling, volunteer unrelated donors or partially mismatched related donors (PMRD), stored cord ...

    Clinical Trial last updated 04/27/2016 - 9:59am.

  10. CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

    ... of blood cells in the body) are selected (removed) from the donor's peripheral blood stem cells. In doing this, T-cells (a type of blood ... blood stem cell transplant from a family member or adult unrelated donor . To determine how often primary graft failure and ...

    Clinical Trial last updated 04/28/2016 - 8:36am.