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  1. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... physician immediately Research participants must have a donor or stem cell source identified for allogeneic transplantation, either related (7/8 or 8/8 allele matched or haploidentical), unrelated (7/8 or 8/8 allele match) donor, or cord blood stem cell source (at ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  2. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... myeloid leukemia, or chronic myelogenous leukemia undergoing donor peripheral blood stem cell transplant . Giving chemotherapy ... -matched (HLA-A, B, C, and DRB1 molecularly matched) unrelated donor or related donor capable of donating PBSC DONOR ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  3. RIC Transplant Using Haplo Donors

    ... No available matched related or unrelated donor , OR a matched related or unrelated donor will not be available in ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  4. Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies

    ... malignancies who lack a suitably matched related or unrelated donor . The methodology will be one that has been successfully utilized in ...

    Clinical Trial last updated 04/29/2016 - 10:59am.

  5. Frequently Asked Questions about Bone Marrow Transplants

    ... What is the difference between a related and an unrelated donor ? What is the process of a bone marrow transplant ? What ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  6. Cord Blood Transplant

    ... Human Leukocyte Antigen ( HLA ) matched sibling donor is the most commonly used source of allogeneic stem cells . ... SCT. In the absence of an HLA matched sibling, volunteer unrelated donors or partially mismatched related donors (PMRD), stored cord ...

    Clinical Trial last updated 04/27/2016 - 9:59am.

  7. CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

    ... of blood cells in the body) are selected (removed) from the donor's peripheral blood stem cells. In doing this, T-cells (a type of blood ... blood stem cell transplant from a family member or adult unrelated donor . To determine how often primary graft failure and ...

    Clinical Trial last updated 04/28/2016 - 8:36am.

  8. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... in Table 2.4a) Patients must have a related or unrelated peripheral blood stem cell donor as follows: Sibling donor must be a 6/6 match for HLA -A and ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  9. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... B, and C and HLA Class II DRB1 and DQB1 alleles. Unrelated donor : An 8/10, 9/10 or 10/10 matched unrelated adult donor (MUD) will be ...

    Clinical Trial last updated 06/13/2016 - 2:06pm.

  10. Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

    ... after a period of improvement (relapsed) undergoing a second donor stem cell transplant . IMTMI is a type of radiation therapy to the ... the donor could be matched related donors or matched unrelated donors from registry DONOR: If more than one potential ...

    Clinical Trial last updated 05/23/2016 - 2:06pm.