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  1. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... a transplant utilizing mis-matched related or matched unrelated donors following a preparative regimen of busulfan, fludarabine ... human leukocyte antigen ( HLA ) compatible unrelated or HLA-genotypically matched related donors (no fully matched sibling donor). Patients and donors may be of either gender or any ethnic ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  2. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... have become cancer. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving ... years who have a 7-8/8 HLA -A,B,C,DRB1 allele matched unrelated volunteer marrow and/or peripheral blood stem cell (PBSC) donor match ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  3. Intra-Osseous Co-Transplant of UCB and hMSC

    ... This clinical trial studies intra-osseous donor umbilical cord blood and mesenchymal stromal cell co-transplant in ... (defined as matched in HLA A, B, C, and DRB1) related or unrelated donors Cord Blood Units available through NMDP with the ...

    Clinical Trial last updated 05/02/2016 - 11:15am.

  4. Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR

    ... hematopoietic stem cell transplantation from a related or unrelated HLA matched donor. The effect of 5-azacytidine on global gene methylation will be ...

    Clinical Trial last updated 05/02/2016 - 11:10am.

  5. Allogenic stem cell transplantation for older patients with AML and MDS

    ... The term “allogeneic” refers to a transplant from a donor who is someone other than himself or herself; rather the donor is someone with a different immune system such as a sibling or an unrelated person. This type of transplant works by supplying the patient with ...

    Research Review last updated 05/02/2016 - 9:31am.

  6. Transplants With Unlicensed Preserved Cord Blood

    ... outline safety and effectiveness requirements for cells from unrelated donors or when HCT/Ps are more than minimally manipulated, assure ... and distribution protocol conducted by the National Marrow Donor Program (NMDP) for unlicensed cryopreserved cord blood units (CBUs) in ...

    Clinical Trial last updated 04/27/2016 - 3:20pm.

  7. Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia.

    ... CSA treatment and lacked a HLA -matched sibling donor, underwent co-transplantation of unrelated donor peripheral blood stem cells (UD-PBSCs) and ...

    Research Article last updated 11/26/2013 - 11:14am.

  8. Abatacept Reduced Intensity for Non-Malignant Diseases (Aba NMD)

    ... mortality from graft versus host disease (GVHD), driven by donor T cells recognizing and reacting against disparate host antigens. This ... mofetil, to improve disease-free survival after unrelated hematopoietic stem cell transplantation (HSCT) using low dose total ...

    Clinical Trial last updated 04/27/2016 - 2:40pm.

  9. MDS Patient Becomes a Role Model

    ... and radiation followed by a bone marrow transplant from an unrelated, 10 out of 10 match, donor. I recently had my one-year transplant anniversary. For over a year, ...

    Patient Chronicle last updated 04/22/2016 - 5:19pm.

  10. Allogeneic BM transplantation for the treatment of aplastic anemia: current results and expanding donor possibilities

    ... BM transplantation from an HLA -identical sibling donor leads to long-term survival in the majority of patients (> 80%). ... a sibling donor, transplantation from a well-matched unrelated donor can be considered after failure of a previous course of ...

    Research Article last updated 01/07/2014 - 12:31pm.