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  1. Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR

    ... hematopoietic stem cell transplantation from a related or unrelated HLA matched donor. The effect of 5-azacytidine on global gene methylation will be ...

    Clinical Trial last updated 05/02/2016 - 11:10am.

  2. Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia

    ... stem cell transplant using related or unrelated donor in persons 0-70 years of age diagnosed with dyskeratosis ... preparative regimens are included based on disease and donor type. Status:  ...

    Clinical Trial last updated 04/25/2016 - 10:59am.

  3. Allogenic stem cell transplantation for older patients with AML and MDS

    ... The term “allogeneic” refers to a transplant from a donor who is someone other than himself or herself; rather the donor is someone with a different immune system such as a sibling or an unrelated person. This type of transplant works by supplying the patient with ...

    Research Review last updated 05/02/2016 - 9:31am.

  4. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... did not occur, with all patients achieving complete donor lymphohematopoietic chimerism. Unfortunately, recipients of G-CSF ... PBSC co-infused with a reduced dose of non-mobilized donor T-cells that have not undergone a TH-2 cytokine polarization. ... from an HLA identical sibling or match unrelated donor using the identical conditioning regimen utilized in ...

    Clinical Trial last updated 04/25/2016 - 10:08am.

  5. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... is a condition that results from a reaction of transplanted donor T-lymphocytes against the body and organs of the patient receiving the ... AlloSCT from either a partially matched family member or an unrelated adult stem cell transplant donor. The transplanted cells will allow ...

    Clinical Trial last updated 04/27/2016 - 8:55am.

  6. Transplants With Unlicensed Preserved Cord Blood

    ... outline safety and effectiveness requirements for cells from unrelated donors or when HCT/Ps are more than minimally manipulated, assure ... and distribution protocol conducted by the National Marrow Donor Program (NMDP) for unlicensed cryopreserved cord blood units (CBUs) in ...

    Clinical Trial last updated 04/27/2016 - 3:20pm.

  7. Abatacept Reduced Intensity for Non-Malignant Diseases (Aba NMD)

    ... mortality from graft versus host disease (GVHD), driven by donor T cells recognizing and reacting against disparate host antigens. This ... mofetil, to improve disease-free survival after unrelated hematopoietic stem cell transplantation (HSCT) using low dose total ...

    Clinical Trial last updated 04/27/2016 - 2:40pm.

  8. MDS Patient Becomes a Role Model

    ... and radiation followed by a bone marrow transplant from an unrelated, 10 out of 10 match, donor. I recently had my one-year transplant anniversary. For over a year, ...

    Patient Chronicle last updated 04/22/2016 - 5:19pm.

  9. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... event-free survival to 30% to 50% in the alternative donor (matched unrelated, partially matched family member) transplantation. Although an ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  10. Bone Marrow Transplant

    ... cell transplants. A transplant may use cells taken from a donor or from the patient: Autologous transplants use a patient's ... donor. These might come from a sibling, or a matched unrelated donor (MUD). The donor's tissue type must be a suitable match ...

    Topic section last updated 03/29/2016 - 7:27pm.