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  1. T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts (MOHEL)

    ... Unfortunately, there is not a perfectly matched stem cell donor (like a sister or brother) and the subject's disease is considered ... In recipients of mismatched family member or matched unrelated donor stem cell transplants, there is a greater risk of GVHD so ...

    Clinical Trial last updated 04/28/2016 - 12:15pm.

  2. Bone Marrow and Stem Cell Transplantation

    ... stem cell transplant , you should start looking for a donor now. It can take a long time to find a matched donor. This section ... donor . And it can take a long time to find a matched unrelated donor if no related donor is available. How does the search ...

    Page last updated 09/30/2014 - 11:47am.

  3. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... or ethnic background. Prior transfusions from selected donor (as this could have cause recipient alloimmunization against the donor) Women of childbearing potential who currently are pregnant (HCG+) or ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  4. Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

    ... designed to block participant's body's ability to reject the donor's stem cells . Researchers also want to learn if giving AP1903 ... -matched for HLA-A, -B, C and DR matched or, b. Matched Unrelated Donor (MUD), 8/8 HLA-matched for HLA A, B, C and DRB1 using ...

    Clinical Trial last updated 06/06/2016 - 12:41pm.

  5. HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

    ... subject and must sign an informed consent form.   Donor Inclusion Criteria: Each donor must meet criteria outlined by institutional guidelines Donor should ...

    Clinical Trial last updated 04/29/2016 - 3:18pm.

  6. Overview of stem cell transplantation for aplastic anemia

    ... stem cells taken from another person, known as the donor source or source of the graft. The donor can be the patient’s brother ... patient does not have a matched sibling or related donor, an unrelated individual that shares important genetic similarities with the ...

    Research Review last updated 05/02/2016 - 9:31am.

  7. Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301)

    ... in Table 2.4) Patients must have a related or unrelated donor as follows: Related donor must be an 8/8 match for human ...

    Clinical Trial last updated 06/06/2016 - 1:36pm.

  8. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... readily available consenting HLA - matched related donor who is either matched fully matched or mismatched at only one locus ... of a readily available HLA-matched volunteer unrelated donor (8 of 8 allele match at HLA-A, -B, -C and -DRB1). ...

    Clinical Trial last updated 06/06/2016 - 3:37pm.

  9. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... readily available consenting HLA - matched related donor who is either matched fully matched or mismatched at only one locus ... of a readily available HLA-matched volunteer unrelated donor (8 of 8 allele match at HLA-A, -B, -C and -DRB1). ...

    Clinical Trial last updated 06/03/2016 - 2:54pm.

  10. The Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plus Unrelated Cord Donor Search Versus Matched Unrelated Donor Search For AML And High-Risk MDS Patients

    ... older, randomized between haplo-cord search and matched unrelated donor (MUD) search for patients with acute myeloid leukemia (AML) and ...

    Clinical Trial last updated 04/29/2016 - 2:02pm.