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  1. Diagnosis and Treatment of Aplastic Anemia

    ... number of factors including AA severity, age of the patient, donor availability, and access to optimal therapies. For newly diagnosed severe ... therapy include encouraging results with closely matched unrelated donor transplants in younger patients and the emerging benefits ...

    Research Article last updated 12/06/2017 - 8:45am.

  2. Repurposing older drugs to help prevent GVHD

    ... to prevent GVHD after myeloablative conditioning, unrelated donor HCT Article Source:  Web ...

    Article last updated 10/18/2017 - 8:48am.

  3. Haploidentical Hematopoietic Cell Transplant with Post-Transplant Cyclophosphamide and Peripheral Blood Stem Cell Grafts in Older Adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome

    ... haploidentical (haplo) donors have dramatically expanded the donor pool for patients requiring HCT. Initial studies were performed with ... patient age ≥ 65 undergoing HLA -matched unrelated donor (MUD) HCT for AML or MDS during the same time frame. ...

    Research Article last updated 11/14/2017 - 10:09am.

  4. Drug reduces acute GVHD in unrelated HSCTs

    ... Vorinostat Lowers Acute GVHD in Patients Receiving Unrelated Donor HSCT Article Source:  ...

    Article last updated 02/27/2017 - 1:45pm.

  5. SAA patient finds unrelated donor match in 2 weeks

    ... meet. He was notified in late February that a marrow donor who lives in the United States had been found after just two weeks and ... people searching for a lifesaving match never get an unrelated donor who might cure them of their disease or cancer. ...

    Article last updated 03/21/2017 - 11:19am.

  6. Allogeneic transplant: does age still matter?

    ... improved HLA matching. Despite an increase in unrelated donor availability, the CIBMTR has estimated that only 26% of eligible ...

    Article last updated 08/31/2017 - 2:17pm.

  7. Unrelated cord blood transplantation in a child with very severe aplastic anemia

    ... Recently, bone marrow transplantation from an unrelated donor has been recommended as an option for the treatment of very severe ...

    Research Article last updated 02/04/2013 - 1:41pm.

  8. Successful treatment of aplastic anemia-paroxysmal nocturnal hemoglobinuria associated with eosinophilic fasciitis with matched unrelated donor allogeneic peripheral blood stem cell transplantation

    ... blood stem cell transplantation from a matched unrelated donor after multiple immunosuppressant failure. ...

    Research Article last updated 09/13/2016 - 12:49pm.

  9. Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis

    ... younger than 40 years, with a HLA identical sibling donor. For patients older than 40 years, IST was the only therapeutic option. ... two decades, the improved results in the setting of unrelated donor (UD) transplantation have allowed us to introduce UD HSCT ...

    Research Article last updated 03/03/2015 - 11:27am.

  10. Outcome of patients activating an unrelated donor search for severe acquired aplastic anemia.

    ... with severe aplastic anemia (SAA) without a sibling donor receive immunosuppressive treatment (IST) with anti-thymocyte globulin (ATG). In the case of no response to IST, a voluntary unrelated donor (VUD) search is usually started. This study analyzes the ...

    Research Article last updated 07/09/2013 - 2:50pm.