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  1. A retrospective study of paroxysmal nocturnal hemoglobinuria in pediatric and adolescent patients

    ... Moreover, our study showed that any case of unexpected thrombosis represents a criterium to perform a PNH screening. ...

    Research Article last updated 05/02/2017 - 10:42am.

  2. Treating Blood Clots

    Blood clots are very dangerous. If you have a blood clot , you need to get help right away. Here are some ways blood clots are treated. Blood Thinners Blood thinners are the most common way to treat ...

    Page last updated 01/20/2015 - 4:58pm.

  3. The dysfunction of platelets in paroxysmal nocturnal hemoglobinuria

    ... INTRODUCTION: Thrombosis is a dangerous complication of paroxysmal nocturnal ... rate. However, the mechanism underlying the development of thrombosis in PNH remains unclear. To explore this, platelet function ...

    Research Article last updated 11/02/2016 - 10:37am.

  4. Positive Impact of Eculizumab Therapy on Surgery for Budd-Chiari Syndrome in a Patient with Paroxysmal Nocturnal Hemoglobinuria and a Long-Term History of Thrombosis

    ... with severe end-organ damage and a high risk of thrombosis . Budd-Chiari syndrome , which develops after thrombotic ...

    Research Article last updated 11/02/2016 - 2:49pm.

  5. Paroxysmal Nocturnal Hemoglobinuria: From Bench to Bed

    ... a variety of clinical manifestations, such as anemia, thrombosis , kidney disease, smooth muscle dystonias, abdominal pain, ...

    Research Article last updated 11/28/2016 - 11:40am.

  6. Pathogenesis of paroxysmal nocturnal hemoglobinuria

    ... from complement attack. Hemolytic anemia , venous thrombosis , and bone marrow failure are thus the resulting triad of ...

    Research Article last updated 11/02/2016 - 2:52pm.

  7. Efficacy and Safety of Lenalidomide for Treatment of Low-/Intermediate-1-Risk Myelodysplastic Syndromes with or without 5q Deletion: A Systematic Review and Meta-Analysis

    ... , leukopenia, anemia , deep vein thrombosis , diarrhea, fatigue and rash were 51% (95% CI 30-73%), 31% (95% ...

    Research Article last updated 11/28/2016 - 9:36am.

  8. Allogeneic hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: a retrospective single-center study

    ... a significant relationship between a positive history of thrombosis and a higher mortality rate. HSCT has curative role in ...

    Research Article last updated 11/02/2016 - 10:41am.

  9. Antonio Maria Risitano, MD, PhD

    ... Pathophysiology , Clinical Manifestations (including Thrombosis ) and Response to Eculizamab PNH Foundation." We recently ...

    Bio last updated 10/20/2017 - 9:50am.

  10. Diagnostic screening of paroxysmal nocturnal hemoglobinuria: Prospective multicentric evaluation of the current medical indications

    ... been submitted for PNH testing because of unexplained thrombosis in the absence of cytopenia , were positive (0.4%). ... screening algorithms are needed for patients presenting with thrombosis and normal blood cell counts. ...

    Research Article last updated 10/06/2016 - 8:56am.