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  1. T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

    ... , bone marrow (BM) failure, and venous thrombosis . The etiology of PNH is a somatic mutation in ...

    Research Article last updated 07/11/2017 - 10:43am.

  2. A retrospective study of paroxysmal nocturnal hemoglobinuria in pediatric and adolescent patients

    ... Moreover, our study showed that any case of unexpected thrombosis represents a criterium to perform a PNH screening. ...

    Research Article last updated 05/02/2017 - 10:42am.

  3. “Don’t worry, I’m not going anywhere.”

    ... blurred vision and has developed sleep apnea, deep vein thrombosis , and herniated and bulging neck and spine discs due to ...

    Patient Chronicle last updated 04/26/2018 - 10:18am.

  4. The dysfunction of platelets in paroxysmal nocturnal hemoglobinuria

    ... INTRODUCTION: Thrombosis is a dangerous complication of paroxysmal nocturnal ... rate. However, the mechanism underlying the development of thrombosis in PNH remains unclear. To explore this, platelet function ...

    Research Article last updated 11/02/2016 - 10:37am.

  5. Positive Impact of Eculizumab Therapy on Surgery for Budd-Chiari Syndrome in a Patient with Paroxysmal Nocturnal Hemoglobinuria and a Long-Term History of Thrombosis

    ... with severe end-organ damage and a high risk of thrombosis . Budd-Chiari syndrome , which develops after thrombotic ...

    Research Article last updated 11/02/2016 - 2:49pm.

  6. Paroxysmal nocturnal hemoglobinuria in pediatric patients.

    ... marrow failure , intravascular hemolysis , and thrombosis . To further characterize the clinical presentation and outcome ... excessive blasts or leukemic transformation. Thrombosis occurred in 6 patients. Five patients underwent hematopoietic ...

    Research Article last updated 12/12/2011 - 10:07am.

  7. Paroxysmal Nocturnal Hemoglobinuria: From Bench to Bed

    ... a variety of clinical manifestations, such as anemia, thrombosis , kidney disease, smooth muscle dystonias, abdominal pain, ...

    Research Article last updated 11/28/2016 - 11:40am.

  8. Pathogenesis of paroxysmal nocturnal hemoglobinuria

    ... from complement attack. Hemolytic anemia , venous thrombosis , and bone marrow failure are thus the resulting triad of ...

    Research Article last updated 11/02/2016 - 2:52pm.

  9. Allogeneic hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: a retrospective single-center study

    ... a significant relationship between a positive history of thrombosis and a higher mortality rate. HSCT has curative role in ...

    Research Article last updated 11/02/2016 - 10:41am.

  10. Efficacy and Safety of Lenalidomide for Treatment of Low-/Intermediate-1-Risk Myelodysplastic Syndromes with or without 5q Deletion: A Systematic Review and Meta-Analysis

    ... , leukopenia, anemia , deep vein thrombosis , diarrhea, fatigue and rash were 51% (95% CI 30-73%), 31% (95% ...

    Research Article last updated 11/28/2016 - 9:36am.