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  1. Paroxysmal nocturnal hemoglobinuria in pediatric patients.

    ... and jaundice , hepatitis, and isolated thrombocytopenia (N = 1). Immunosuppressive therapy was the initial ...

    Research Article last updated 12/12/2011 - 10:07am.

  2. The clinical safety of lenalidomide in multiple myeloma and myelodysplastic syndromes

    ... including dose modifications for neutropenia and thrombocytopenia , and venous thromboembolism prophylaxis, where applicable, ...

    Research Article last updated 11/16/2011 - 2:10pm.

  3. Novel approaches for myelodysplastic syndromes: beyond hypomethylating agents.

    ... has shown promising results in the treatment of thrombocytopenia . However, determination of an optimal chemotherapeutic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Simona Pagliuca, MD

    ... ), white blood cells (leukopenia), and platelets ( thrombocytopenia ). If untreated, this disease has a high risk of death. ... ), white blood cells (leukopenia), and platelets ( thrombocytopenia ). If untreated, this disease has a high risk of severe ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  5. Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes.

    ... Grade 3-4 anemia , neutropenia , and thrombocytopenia with AZA vs CCR were 13% vs 4%, 61% vs 17%, and 50% vs ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Randomized Phase III Study of Lenalidomide Versus Placebo in RBC Transfusion-Dependent Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents

    ... adverse events were neutropenia and thrombocytopenia . CONCLUSION: Lenalidomide yields sustained RBC-TI ...

    Research Article last updated 07/18/2016 - 10:30am.

  7. How we treat lower risk myelodysplastic syndromes.

    ... agonists are under investigation in lower risk MDS with thrombocytopenia . Some patients, while remaining "lower risk" MDS, have ...

    Research Article last updated 05/14/2013 - 2:56pm.

  8. 5-Azacitidine efficacy and safety in patients aged >65 years with myelodysplastic syndromes outside clinical trials

    ... experienced hematologic side effects (25% grade 3-4 thrombocytopenia and 30% grade 3-4 neutropenia ). Our results ...

    Research Article last updated 06/15/2012 - 2:13pm.

  9. Predictors of Hemoglobin Response to Eculizumab Therapy in Paroxysmal Nocturnal Hemoglobinuria

    ... trials of eculizumab due to lack of transfusions or thrombocytopenia ; eight had at least a good partial response. ...

    Research Article last updated 11/05/2012 - 10:28am.

  10. Clinical effect of point mutations in myelodysplastic syndromes

    ... TP53, and NRAS were most strongly associated with severe thrombocytopenia (P<0.001 for all comparisons) and an increased proportion ...

    Research Article last updated 10/11/2011 - 5:58pm.