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  1. Identifying bone marrow failure in children

    ... potentially life-threatening infections. Children with thrombocytopenia might bruise easily and have nosebleeds. In an ...

    Article last updated 03/15/2017 - 10:08am.

  2. Simona Pagliuca, MD

    ... ), white blood cells (leukopenia), and platelets ( thrombocytopenia ). If untreated, this disease has a high risk of death. ... ), white blood cells (leukopenia), and platelets ( thrombocytopenia ). If untreated, this disease has a high risk of severe ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  3. Treatment of low-risk myelodysplastic syndromes

    ... frequently presenting as isolated. Specific therapy for thrombocytopenia has been proposed in experimental clinical trials with ...

    Research Article last updated 01/26/2017 - 10:42am.

  4. Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

    ... than progression to acute myeloid leukemia. Severe thrombocytopenia , although less common in lower-risk MDS, is associated ...

    Research Article last updated 12/09/2016 - 2:50pm.

  5. Molecular Testing in Patients with Suspected Myelodysplastic Syndromes

    ... clinically with leukopenia, anemia , and/or thrombocytopenia and with a propensity to transform to acute ...

    Research Article last updated 11/02/2016 - 10:09am.

  6. Efficacy and Safety of Lenalidomide for Treatment of Low-/Intermediate-1-Risk Myelodysplastic Syndromes with or without 5q Deletion: A Systematic Review and Meta-Analysis

    ... The incidences of grades 3-4 neutropenia , thrombocytopenia , leukopenia, anemia , deep vein thrombosis , ...

    Research Article last updated 11/28/2016 - 9:36am.

  7. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... poor prognostic features including anemia and/or thrombocytopenia who may have required red blood cell or ... with red blood cell (RBC) transfusion-dependent anemia and thrombocytopenia. Eligible patients are randomized 1:1 to receive 300 mg of ...

    Research Article last updated 06/23/2016 - 10:17am.

  8. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... has been approved by the FDA for treating chronic immune thrombocytopenia (ITP) How does it work? It appears to ...

    Interview last updated 07/06/2012 - 3:42pm.

  9. Azacitidine-lenalidomide (ViLen) combination yields a high response rate in higher risk myelodysplastic syndromes (MDS)-ViLen-01 protocol

    ... in these patients: grades III-IV, mainly hematologic- thrombocytopenia (20 patients) and neutropenia (13 patients). The ...

    Research Article last updated 09/13/2016 - 2:47pm.

  10. Randomized Phase III Study of Lenalidomide Versus Placebo in RBC Transfusion-Dependent Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents

    ... adverse events were neutropenia and thrombocytopenia . CONCLUSION: Lenalidomide yields sustained RBC-TI ...

    Research Article last updated 07/18/2016 - 10:30am.