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  1. Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single-blind, randomised, controlled, phase 2 superiority trial.

    ... BACKGROUND: In myelodysplastic syndromes , thrombocytopenia is associated with mortality, but treatments in this ... receptor agonist, might be effective in improving thrombocytopenia in lower-risk myelodysplastic syndromes and severe thrombocytopenia. METHODS: EQoL-MDS was a single-blind, randomised, ...

    Research Article last updated 02/21/2017 - 9:49am.

  2. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... were developed to treat patients with refractory immune thrombocytopenia but are now being investigated for the treatment of bone ...

    Research Article last updated 06/20/2013 - 10:13am.

  3. Left main crossover stenting in a patient with severe thrombocytopenia due to aplastic anemia

    ... treatment/transfusion alone because of severe thrombocytopenia and anemia ( platelet 11 × 103/μL, ...

    Research Article last updated 12/09/2016 - 2:08pm.

  4. ASCO Updates Platelet Transfusion Guideline Prophylaxis unnecessary for adults undergoing HSCT

    ... treatment of bleeding in patients with treatment-related thrombocytopenia but also sought to avoid the overuse of platelet ... the risk of bleeding from chemotherapy -induced thrombocytopenia in patients with solid tumors - a platelet threshold of <10 x ...

    Research Article last updated 12/06/2017 - 11:23am.

  5. Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

    ... The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding risk. Splenectomy could alleviate ...

    Research Article last updated 04/17/2014 - 1:34pm.

  6. Thrombocytopenia in patients with myelodysplastic syndromes.

    ... July 1, 2010 Thrombocytopenia , common in leukemias and myelodysplastic syndromes ... purpura (ITP), and are being explored for the treatment of thrombocytopenia in MDS. Bone Marrow Diseases:  ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Foundation Update - January 2017

    ... a variety of blood conditions including anemia , thrombocytopenia , and myelodysplastic syndrome. Read Dr. Friedman's remarks ...

    Article last updated 10/09/2017 - 2:44pm.

  8. Thrombopoiesis-stimulating agents and myelodysplastic syndromes

    ... 6, 2015 Thrombocytopenia in patients with myelodysplastic syndromes (MDS) ... transformation and reduced overall survival. In addition, thrombocytopenia in MDS limits the tolerability and therapeutic efficacy of ...

    Research Article last updated 03/04/2015 - 10:20am.

  9. Romiplostim monotherapy in thrombocytopenic patients with myelodysplastic syndromes: long-term safety and efficacy

    ... (lower risk) myelodysplastic syndromes (MDS) and thrombocytopenia , but its long-term toxicity and efficacy are not known. ...

    Research Article last updated 07/11/2017 - 10:22am.

  10. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of thrombopoietin receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO ... in fatigue and exacerbation of heart conditions, and thrombocytopenia in bleeding. Bone marrow transplantation is the only ...

    Research Review last updated 05/02/2016 - 9:21am.