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  1. Allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes

    ... with curative potential for myelodysplastic syndrome (MDS). The availability of SCT has been expanded with the introduction of ... with intermediate-2 and high-risk disease and those with therapy-related MDS have a poor prognosis with alternative therapies; ...

    Research Article last updated 01/07/2014 - 9:50am.

  2. Role of Reduced-Intensity Conditioning Allogeneic Hematopoietic Stem-Cell Transplantation in Older Patients With De Novo Myelodysplastic Syndromes: An International Collaborative Decision Analysis.

    ... PURPOSEMyelodysplastic syndromes (MDS) are clonal hematopoietic disorders that are more common in patients aged ... leukemia, isolated 5q- syndrome, unclassifiable, and therapy-related MDS were excluded. Transplantation using T-cell depletion ...

    Research Article last updated 07/09/2013 - 3:28pm.

  3. The National Myelodysplastic Syndromes Natural History Study

    ... or newly diagnosed with myelodysplastic syndromes (MDS), myelodysplastic syndromes/myeloproliferative neoplasms (MDS/MPN) overlap ... assessments, or diagnosed with de novo or therapy-related MDS within 6-months of enrollment per the World Health ...

    Clinical Trial last updated 02/23/2017 - 1:36pm.

  4. Total Lymphoid Irradiation-Antithymocyte Globulin Conditioning and Allogeneic Transplantation for Patients with Myelodysplastic Syndromes and Myeloproliferative Neoplasms

    ... curative therapy for the myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN), but treatment toxicity has been a ... to treat 61 patients with allo HCT for MDS (n = 32), therapy-related myeloid neoplasms (n = 15), MPN (n = 9), and chronic ...

    Research Article last updated 04/17/2014 - 11:48am.

  5. What is Secondary MDS? Everything You Need to Know

    ... Treatment-related MDS, also known as secondary MDS , makes up a small fraction of cases of ... with another primary bone marrow disorder vs. therapy-related MDS ) How to play an active role in your care by ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  6. What is Secondary MDS? Everything You Need to Know

    ... Treatment-related MDS, also known as secondary MDS , makes up a small fraction of cases of ... with another primary bone marrow disorder vs. therapy-related MDS ) How to play an active role in your care by ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  7. Prediction of outcomes after allogeneic stem cell transplantation for myelodysplastic syndromes

    ... to the recipient) is still the only potential cure for MDS patients.  However, an aBMT may cause serious complications, some of which ... poor to very poor scores in that same scoring system, therapy-related MDS (i.e., MDS that is associated with prior anti-cancer ...

    Research Review last updated 05/02/2016 - 9:29am.

  8. Causes

    ... De Novo MDS The cause of most MDS cases is ... novo MDS. You may also hear doctors call this: Therapy-related MDS Secondary MDS On average, ...

    Topic section last updated 03/10/2016 - 10:59pm.

  9. UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

    ... myelodysplastic syndromes (MDS) Associated Drug(s):  ... risk cytogenetics based on IPSS or R-IPSS definitions; therapy-related MDS . Blasts must be < 5% by a representative bone ...

    Clinical Trial last updated 04/29/2016 - 10:06am.

  10. Allo HSCT Using RIC for Hematological Diseases

    ... myelodysplastic syndromes (MDS) Phase:  ... risk cytogenetics based on IPSS or R-IPSS definitions; therapy-related MDS . Blasts must be < 5% by bone marrow aspirate ...

    Clinical Trial last updated 05/02/2016 - 9:29am.