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  1. Allogeneic stem cell transplantation in therapy-related acute myeloid leukemia and myelodysplastic syndromes: impact of patient characteristics and timing of transplant

    ... Patients with therapy-related acute myeloid leukemia (t-AML) and myelodysplastic syndromes (t-MDS) have poor survival and high non-relapse mortality (NRM) after allogeneic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Radiation alone for solid tumors and the questionable development of therapy-related myelodysplastic syndromes

    ... myelodysplastic syndromes (MDS) ...

    Research Article last updated 04/09/2014 - 9:55am.

  3. Application of the International Prognostic Scoring System-Revised (IPSS-R) in Therapy-related Myelodysplastic Syndromes and Oligoblastic Acute Myeloid Leukemia.

    ... myelodysplastic syndromes (MDS) ...

    Research Article last updated 06/28/2013 - 1:22pm.

  4. Causes

    ... De Novo MDS The cause of most MDS cases is ... MDS. You may also hear doctors call this: Therapy-related MDS Secondary MDS On average, ...

    Topic section last updated 04/06/2018 - 12:27pm.

  5. New study hails test to weigh SCT for MDS

    ... can indicate which patients with myelodysplastic syndrome (MDS) are likely to benefit from a stem cell transplant , and the ... whose MDS arose as a result of previous cancer therapy ( therapy-related MDS ). They found that TP53 mutations and mutations in ...

    Article last updated 02/09/2017 - 9:03am.

  6. Therapy-related Myelodysplastic Syndrome: an analysis of 5 risk models in patients treated with azacitidine

    ... Myelodysplastic syndrome (MDS) is a disease mostly associated with old age, however, it can also occur as ... chemotherapies and/or radiation.  This is called therapy-related MDS (t-MDS).  When it happens it is often an aggressive ...

    Research Review last updated 05/02/2016 - 9:28am.

  7. Mesenchymal stromal cell density is increased in higher grade myelodysplastic syndromes and independently predicts survival

    ... to evaluate for myelodysplastic syndromes (MDS). METHODS: CD271+ MSC density was quantitated by automated image ... Scoring System (IPSS-R), history of transfusion, therapy-related MDS , and fibrosis (hazard ratio, 3.4; P < .001). ...

    Research Article last updated 11/25/2014 - 8:57am.

  8. Allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes

    ... with curative potential for myelodysplastic syndrome (MDS). The availability of SCT has been expanded with the introduction of ... with intermediate-2 and high-risk disease and those with therapy-related MDS have a poor prognosis with alternative therapies; ...

    Research Article last updated 01/07/2014 - 9:50am.

  9. Mayo Clinic links MDS with autoimmune drug

    ... a decade at Mayo Clinic. They identified 86 patients with therapy-related myeloid neoplasm. Detailed data on each patient's drug ... significantly associated with an increased risk of therapy-related myeloid neoplasm. However, other agents used showed a similar ...

    Article last updated 02/03/2017 - 1:19pm.

  10. Role of Reduced-Intensity Conditioning Allogeneic Hematopoietic Stem-Cell Transplantation in Older Patients With De Novo Myelodysplastic Syndromes: An International Collaborative Decision Analysis.

    ... PURPOSEMyelodysplastic syndromes (MDS) are clonal hematopoietic disorders that are more common in patients aged ... leukemia, isolated 5q- syndrome, unclassifiable, and therapy-related MDS were excluded. Transplantation using T-cell depletion ...

    Research Article last updated 07/09/2013 - 3:28pm.