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  1. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... How do you currently think about the role of stem cell transplantation in aplastic anemia ? This is an exciting ... have to also deal with the risk of relapse of the malignant cells. Relapsed MDS or AML is much more challenging to cure. It all just ...

    Interview last updated 11/28/2016 - 2:58pm.

  2. Swabbing leaps into the record books, sort of

    ... have already donated either bone marrow or blood stem cells to save the life of someone with cancer, and to encourage more people ...

    Article last updated 10/04/2016 - 2:38pm.

  3. A plasma microRNA signature as a biomarker for acquired aplastic anemia

    ... by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack ...

    Research Article last updated 10/06/2016 - 9:39am.

  4. David Araten, MD

    ... understood in PNH includes the  expansion of an abnormal stem cell clone in the bone marrow (called clonal expansion) which can ... provide a very large percentage of the patient's blood cells. This clone has as its feature the presence of a mutation in a ...

    Grant Recipient last updated 11/30/2016 - 10:51am.

  5. Mutations of myelodysplastic syndromes (MDS): An update

    ... a heterogeneous pre-malignant disorder of hematopoietic stem cells , through sequencing of several pathway genes has unveiled molecular ...

    Research Article last updated 09/19/2016 - 11:02am.

  6. Deregulated microRNA expression and its pathogenetic implications for myelodysplastic syndromes

    ... (MDS) include a heterogeneous group of clonal hematological stem cell disorders characterized by ineffective hematopoiesis , ... of the differentiation of hematopoietic stem/progenitor cells. Thus, it is not surprising that dysregulation of miRNAs can lead to ...

    Research Article last updated 08/15/2016 - 11:30am.

  7. Pexmetinib: a novel dual inhibitor of Tie-2 and p38 MAPK with efficacy in preclinical models of myelodysplastic syndromes and acute myeloid leukemia

    ... that elevation of angiopoietin-1 in myelodysplastic CD34+ stem-like cells is associated with higher risk disease and reduced overall survival in ...

    Research Article last updated 07/18/2016 - 11:12am.

  8. Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia

    ... Memory stem T cells (TSCMs) constitute a long-lived, self-renewing lymphocyte ...

    Research Article last updated 04/29/2016 - 12:59pm.

  9. Major news in BMT with half-match donors

    ... Texan is first adult in U.S. to receive updated stem cell transplant for leukemia treatment ... cell transplant that uses genetically engineered blood cells from a family member, announced researchers at UT Southwestern Medical ...

    Article last updated 06/14/2016 - 3:02pm.

  10. AAMDSIF partners on new MDS patient resource

    ... are the result of genetic alterations that cause blood stem cells to become abnormal, rendering bone marrow unable to create ...

    Article last updated 06/28/2016 - 12:43pm.