Search | Page 8 | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition

    ... (PNH) is a rare disease of hematopoietic stem cells due to a mutation in the PIG-A gene leading to a ...

    Research Article last updated 11/05/2013 - 12:37pm.

  2. Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum

    ... complex interactions between primitive hematopoietic stem cells (HSCs) and the extrinsic influences of other cells in the bone ...

    Research Article last updated 04/09/2014 - 9:39am.

  3. Comparison between Matched Related and Alternative Donors of Allogeneic Hematopoietic Stem Cells Transplanted into Adult Patients with Acquired Aplastic Anemia: Multivariate and Propensity Score-Matched Analysis.

    ... anemia (AA) who underwent allogeneic hematopoietic stem cell transplantation (alloHSCT) from matched related donors (MRDs), and ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. How do PIG-A mutant paroxysmal nocturnal hemoglobinuria stem cells achieve clonal dominance?

    Journal Title:  Am J Hematol Primary Author:  Brodsky RA Author(s):  Brodsky ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Announcing AAMDSIF 2016 Research Awards

    ... that changes in the stroma increase beta-catenin in the MDS cells and can be targeted by new drugs. We will utilize mouse models, cells ... inflammation ultimately causes destruction of the stem cells required to maintain daily production of all blood cells. ...

    Article last updated 06/09/2016 - 12:45pm.

  6. A retrospective study of paroxysmal nocturnal hemoglobinuria in pediatric and adolescent patients

    ... Journal Title:  Blood Cells Mol Dis Primary Author:  ... whereas four patients with PNH/BMD underwent hematopoietic stem cell transplantation. Our series confirm that the most frequent ...

    Research Article last updated 05/02/2017 - 10:42am.

  7. Transplant saves student who thought she had mono

    ... where your bone marrow essentially stops producing blood cells for your body. At first, I thought, Fine! I’ll just take a few ... transplant, which replaced my unhealthy blood-forming stem cells with the healthy ones from my donor. The first 100 days ...

    Article last updated 03/06/2017 - 2:37pm.

  8. Updates on the pathophysiology and treatment of aplastic anemia: a comprehensive review.

    ... commentary: Immune-mediated destruction of hematopoietic stem and progenitor cells, leading to a marrow devoid of hematopoietic elements, and peripheral ...

    Research Article last updated 05/02/2017 - 10:13am.

  9. Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria

    ... (PNH) is a nonmalignant clonal disease of hematopoietic stem cells that is associated with hemolysis , marrow failure, and ...

    Research Article last updated 10/02/2014 - 8:24am.

  10. Strong results for SAA patients at Johns Hopkins

    ... one's own immune system damages blood-making bone marrow cells, which gradually stop producing red and white blood cells and platelets. ... immune system cells but does not harm the donor's blood stem cells , which create new disease-free blood cells in the patient. ...

    Article last updated 02/07/2017 - 11:05am.