Search | Page 7 | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... (OS) separately in the 2 arms at 1 year post-hematopoietic stem cell transplantation (HSCT). ... cellularity < 50% but with < 30% residual hematopoietic cells. Two out of three of the following (in peripheral blood): ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  2. Strong results for SAA patients at Johns Hopkins

    ... one's own immune system damages blood-making bone marrow cells, which gradually stop producing red and white blood cells and platelets. ... immune system cells but does not harm the donor's blood stem cells , which create new disease-free blood cells in the patient. ...

    Article last updated 02/07/2017 - 11:05am.

  3. SAA patient finds unrelated donor match in 2 weeks

    ... in which bone marrow does not make enough blood cells. He’s been in and out of hospitals countless times for transfusions ... between 18 and 44, and want to register as a bone marrow/stem cell donor can do it at join.bethematch.org/hope4sarge or ...

    Article last updated 03/21/2017 - 11:19am.

  4. Drug reduces acute GVHD in unrelated HSCTs

    ... donor myeloablative conditioning hematopoietic stem cell transplant (HSCT).1 In a phase II single-arm study, the ... pro-inflammatory cytokines, regulated antigen-presenting cells through induction of indoleamine 2,3-dioxygenase, and enhanced ... higher at day 30 in peripheral blood mononuclear cells from vorinostat-treated patients  compared with similarly treated ...

    Article last updated 02/27/2017 - 1:45pm.

  5. The Myelodysplastic Syndromes: The Era Of Understanding

    ... are a heterogeneous group of clonal haematological stem cell disorders. Allogeneic stem cells transplantation remains the only curative treatment but only a ...

    Research Article last updated 09/24/2014 - 11:05am.

  6. AAMDSIF 2016 Grant Recipients, Part One

    ... between excessive inflammation and the destruction of stem cells that are required to maintain daily production of all blood cells. ...

    Article last updated 10/27/2016 - 12:44pm.

  7. Major news in BMT with half-match donors

    ... Texan is first adult in U.S. to receive updated stem cell transplant for leukemia treatment ... cell transplant that uses genetically engineered blood cells from a family member, announced researchers at UT Southwestern Medical ...

    Article last updated 06/14/2016 - 3:02pm.

  8. The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells

    ... harbor clonal glycosylphosphatidylinositol-anchor deficient cells arising from a multipotent hematopoietic stem cell acquiring a PIG-A mutation . Many patients with aplastic ...

    Research Article last updated 06/15/2012 - 1:48pm.

  9. Pathogenesis of paroxysmal nocturnal hemoglobinuria

    ... of the PIGA gene in one or several hematopoietic stem cells . Recently, PNH caused by somatic mutation of one allele of the PIGT ...

    Research Article last updated 11/02/2016 - 2:52pm.

  10. Announcing AAMDSIF 2016 Research Awards

    ... that changes in the stroma increase beta-catenin in the MDS cells and can be targeted by new drugs. We will utilize mouse models, cells ... inflammation ultimately causes destruction of the stem cells required to maintain daily production of all blood cells. ...

    Article last updated 06/09/2016 - 12:45pm.