Search | Page 6 | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Britta Will, PhD

    ... Therapeutic targeting of aberrant stem cells in MDS Original Research ...

    Grant Recipient last updated 01/12/2018 - 9:48am.

  2. Allogeneic hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: a retrospective single-center study

    ... (PNH) is a rare clonal disease of hematopoietic stem cell characterized by complement mediated intravascular hemolysis . ... plus cyclophosphamide ), and the source of stem cells was peripheral blood of the donors. Mean age at transplant was ...

    Research Article last updated 11/02/2016 - 10:41am.

  3. Study of aplastic anemia med shows significant results

    ... therapies are effective, but reduced numbers of residual stem cells may limit their efficacy. In patients with aplastic anemia that was ...

    Article last updated 04/24/2017 - 7:14am.

  4. Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia

    ... fails to support production of all three lineages of blood cells, which are necessary for tissue oxygenation, infection control, and ... of cases but involves exhaustion of hematopoietic stem cells (HSC), which are usually present in the bone marrow in a dormant ...

    Research Article last updated 10/06/2016 - 9:44am.

  5. Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

    ... which involves active destruction of hematopoietic stem cells and progenitors by cytotoxic T cells in the bone marrow. Aberrant ...

    Research Article last updated 01/24/2017 - 10:08am.

  6. The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells

    ... harbor clonal glycosylphosphatidylinositol-anchor deficient cells arising from a multipotent hematopoietic stem cell acquiring a PIG-A mutation . Many patients with aplastic ...

    Research Article last updated 06/15/2012 - 1:48pm.

  7. Standardized High-Sensitivity Flow Cytometry Testing for Paroxysmal Nocturnal Hemoglobinuria in Children with Acquired Bone Marrow Failure Disorders: A Single Center U.S. Study

    ... hemoglobinuria (PNH) is a rare, acquired hematopoietic stem cell disorder that has not been well documented in children, particularly ... 1% PNH population) and 10 had minor PNH population or rare cells with PNH phenotype (≤ 1% PNH population). CONCLUSIONS: This is ...

    Research Article last updated 06/26/2017 - 9:22am.

  8. Identification of Gene Expression-Based Prognostic Markers in the Hematopoietic Stem Cells of Patients With Myelodysplastic Syndromes.

    ... we have used gene expression profiling (GEP) data on CD34+ cells from patients with MDS to determine the relationship between gene ... prognosis. PATIENTS AND METHODS: GEP data on CD34+ cells from 125 patients with MDS with a minimum 12-month follow-up since date ...

    Research Article last updated 09/09/2013 - 10:45am.

  9. New study hails test to weigh SCT for MDS

    ... Link:  Genetic Profiling Can Guide Stem Cell Transplantation for Patients with Myelodysplastic Syndrome, Study ... report that genetically profiling a patient’s blood cells, while factoring in a patient’s age and other factors, can predict the ...

    Article last updated 02/09/2017 - 9:03am.

  10. Aplastic Anemia & MDS International Foundation: Bone Marrow Failure Disease Scientific Symposium 2014

    ... are characterized by a failure of the hematopoietic stem cells to produce adequate blood cells, resulting in either cytopenia ...

    Research Article last updated 01/23/2015 - 3:36pm.