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  1. AAMDSIF 2016 Grant Recipients, Part One

    ... between excessive inflammation and the destruction of stem cells that are required to maintain daily production of all blood cells. ...

    Article last updated 10/27/2016 - 12:44pm.

  2. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... by development and expansion of self-reactive T cells. These T cells cause continuous destruction of hematopoietic stem cells (HSCs), progenitors, and mature blood cells, leading to severe ...

    Research Article last updated 11/14/2013 - 11:18am.

  3. Cotransplantation of allogeneic mesenchymal and hematopoietic stem cells in children with aplastic anemia

    ... here the preliminary results of allogeneic hematopoietic stem cell transplantation with mesenchymal stem cells (MSCs) for 6 cases of severe aplastic anemia . The patients ...

    Research Article last updated 07/30/2012 - 1:18pm.

  4. Pathogenesis of paroxysmal nocturnal hemoglobinuria

    ... of the PIGA gene in one or several hematopoietic stem cells . Recently, PNH caused by somatic mutation of one allele of the PIGT ...

    Research Article last updated 11/02/2016 - 2:52pm.

  5. The different immunoregulatory functions of mesenchymal stem cells in patients with low-risk or high-risk myelodysplastic syndromes

    ... bone marrow disorders characterized by hematopoietic stem cell dysregulation and abnormalities in the immune system. Mesenchymal stem cells (MSC) have gained further interests after the demonstration of an ...

    Research Article last updated 11/05/2012 - 10:25am.

  6. Functional characteristics of mesenchymal stem cells derived from bone marrow of patients with myelodysplastic syndromes

    ... Mesenchymal stem cells (MSCs) have emerged as excellent candidates for clinical application ...

    Research Article last updated 04/24/2012 - 2:10pm.

  7. Major news in BMT with half-match donors

    ... Texan is first adult in U.S. to receive updated stem cell transplant for leukemia treatment Article ... cell transplant that uses genetically engineered blood cells from a family member, announced researchers at UT Southwestern Medical ...

    Article last updated 06/14/2016 - 3:02pm.

  8. The Myelodysplastic Syndromes: The Era Of Understanding

    ... are a heterogeneous group of clonal haematological stem cell disorders. Allogeneic stem cells transplantation remains the only curative treatment but only a ...

    Research Article last updated 09/24/2014 - 11:05am.

  9. Resources to Help

    ... the needs of patients facing a  bone marrow , blood stem cell or umbilical  cord blood transplant . In addition to high-quality ... the exchange of high quality haematopoietic  stem cells  for clinical transplantation worldwide and to promote the interests of ...

    Topic section last updated 09/28/2017 - 11:58am.

  10. Announcing AAMDSIF 2016 Research Awards

    ... that changes in the stroma increase beta-catenin in the MDS cells and can be targeted by new drugs. We will utilize mouse models, cells ... inflammation ultimately causes destruction of the stem cells required to maintain daily production of all blood cells. ...

    Article last updated 06/09/2016 - 12:45pm.