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  1. Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia.

    ... of unrelated donor peripheral blood stem cells (UD-PBSCs) and umbilical cord mesenchymal/stroma stem cells (UC-MSCs). After FLU + CTX + ATG ± 2GY TBI conditioning, all ...

    Research Article last updated 11/26/2013 - 11:14am.

  2. Kate MacNamara, PhD

    ... inflammation ultimately causes destruction of the stem cells required to maintain daily production of all blood cells. ... are known to contribute to pathology, yet exactly how stem cell function is compromised by these factors is not clear and remains an ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  3. Major news in BMT with half-match donors

    ... Texan is first adult in U.S. to receive updated stem cell transplant for leukemia treatment Article ... cell transplant that uses genetically engineered blood cells from a family member, announced researchers at UT Southwestern Medical ...

    Article last updated 06/14/2016 - 3:02pm.

  4. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... by development and expansion of self-reactive T cells. These T cells cause continuous destruction of hematopoietic stem cells (HSCs), progenitors, and mature blood cells, leading to severe ...

    Research Article last updated 11/14/2013 - 11:18am.

  5. Mutations of myelodysplastic syndromes (MDS): An update

    ... a heterogeneous pre-malignant disorder of hematopoietic stem cells , through sequencing of several pathway genes has unveiled molecular ...

    Research Article last updated 09/19/2016 - 11:02am.

  6. Cotransplantation of allogeneic mesenchymal and hematopoietic stem cells in children with aplastic anemia

    ... here the preliminary results of allogeneic hematopoietic stem cell transplantation with mesenchymal stem cells (MSCs) for 6 cases of severe aplastic anemia . The patients ...

    Research Article last updated 07/30/2012 - 1:18pm.

  7. The different immunoregulatory functions of mesenchymal stem cells in patients with low-risk or high-risk myelodysplastic syndromes

    ... bone marrow disorders characterized by hematopoietic stem cell dysregulation and abnormalities in the immune system. Mesenchymal stem cells (MSC) have gained further interests after the demonstration of an ...

    Research Article last updated 11/05/2012 - 10:25am.

  8. Announcing AAMDSIF 2016 Research Awards

    ... that changes in the stroma increase beta-catenin in the MDS cells and can be targeted by new drugs. We will utilize mouse models, cells ... inflammation ultimately causes destruction of the stem cells required to maintain daily production of all blood cells. ...

    Article last updated 06/09/2016 - 12:45pm.

  9. Functional characteristics of mesenchymal stem cells derived from bone marrow of patients with myelodysplastic syndromes

    ... Mesenchymal stem cells (MSCs) have emerged as excellent candidates for clinical application ...

    Research Article last updated 04/24/2012 - 2:10pm.

  10. Swabbing leaps into the record books, sort of

    ... have already donated either bone marrow or blood stem cells to save the life of someone with cancer, and to encourage more people ...

    Article last updated 10/04/2016 - 2:38pm.