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  1. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... can be obtained in allogeneic blood or bone marrow stem cell transplantation using an human leukocyte antigen ( HLA ... (ATG) Procedure: Adipose derived mesenchymal stem cells ( AD-MSCs) Procedure: AD-MSC transdifferentiated HSCs (AD-HSCs) ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  2. Overlap Syndromes: When PNH Appears with Aplastic Anemia

    ... different reasons. In classic PNH, there is breakdown of red cells and the reticulocyte count is high, but with aplastic anemia, ... to immunotherapy, these cases should be considered for a stem cell transplant . But this only applies if this criteria is used. If ...

    Interview last updated 04/15/2015 - 9:39am.

  3. Clinical Trials Report for June 2015

    ... engraftment with CD3+ /CD19+ depleted peripheral stem cell grafts from mismatched donors. There are two conditioning regimens ... or transplantation of bone marrow or similar blood cells. This study will also help us learn whether a child's age, genetics, or ...

    Page last updated 06/18/2015 - 11:47am.

  4. Clinical Trials Report for May 2015

    ... engraftment with CD3+ /CD19+ depleted peripheral stem cell grafts from mismatched donors. There are two conditioning regimens ... or transplantation of bone marrow or similar blood cells. This study will also help us learn whether a child's age, genetics, or ...

    Page last updated 04/28/2015 - 11:38am.

  5. MDS and MDS/MPN: Past, Present, and Future 2014 American Society of Hematology (ASH) Satellite Symposium Summary for Patients and Families

    ... form and structure of patient blood or bone marrow cells). When used alone, today’s advanced techniques to study genes ... the question Can We Cure Them? The Role of Hematopoietic Stem Cell Transplantation in MDS/MPN.   Treatments for MDS/MPN are ...

    Page last updated 03/13/2015 - 5:00pm.

  6. Clinical Trials Report for July 2015

    ... engraftment with CD3+ /CD19+ depleted peripheral stem cell grafts from mismatched donors. There are two conditioning regimens ... or transplantation of bone marrow or similar blood cells. This study will also help us learn whether a child's age, genetics, or ...

    Page last updated 06/24/2015 - 1:43pm.

  7. B. Douglas Smith, MD

    ... on studying the impact of the treatment on the leukemic stem cell in hopes of limiting these cells’ roles in treatment failure.   Dr. Smith serves on the NCCN ...

    Bio last updated 03/11/2016 - 1:41pm.

  8. Chao-Yie Yang

    ... key proteins that prevent programmed cell death in cancer cells. One compound, AT-406, is currently entering a phase 2 clinical trial ... (GvHD) for treating patients receiving hematopoietic stem cell transplantation with a collaborator at Indiana University. The ...

    Bio last updated 03/11/2016 - 1:41pm.

  9. Interviews with the Experts MDS Genomics: Providing ‘Street View’ Directions of Disease

    ... of each cell, acts as the software program directing how cells grow, divide, sleep or die. Sometimes DNA gets damaged after exposure to toxins or as a normal consequence of aging. If a blood stem cell suffers DNA damage involving a gene important for blood production, ...

    Interview last updated 09/23/2014 - 9:30am.

  10. Pediatric MDS

    ... fi rst spotted as cytopenias (low blood counts). It’s a stem cell disorder in the bone marrow that results in disturbances  in ... relatively low percentage of blasts (immature blood cells in the bone marrow). There’s really no difference in the definition of ...

    Interview last updated 10/24/2012 - 1:31pm.