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  1. Prognostic value of telomere attrition in patients with aplastic anemia

    ... markedly over past 40 years due to advances in hematopoietic stem cell transplantation (HSCT) and immunosuppressive therapy (IST). ... protect the chromosome, when the telomeres are shorter, the cells’ chromosomes are at greater risk for damage and thus disease. Telomeres ...

    Research Review last updated 05/02/2016 - 9:25am.

  2. Adoptive Transfer of Haplo-identical DLI for AML and MDS

    ... may be a tolerable alternative to allogeneic hematopoietic stem cell transplantation (alloHSCT) for elderly patients, the Investigator ... at a dose of 1x10^8 cluster of differentiation 3 (CD3+) cells; however, due to logistics of planning infusions with staffing, donor ...

    Clinical Trial last updated 05/03/2016 - 9:59am.

  3. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... neupogen Biological: Peripheral blood stem cell The source of stem cells for all patients will be peripheral blood stem cells (PBSC) induced and ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  4. Medical Resources

    ... education & awareness about using umbilical cord blood stem cells as a treatment for disease. Salute To Life ...

    Page last updated 08/20/2015 - 8:34am.

  5. SGI-110 With Donor Lymphocyte Infusion (DLI) for Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) Relapsing Post Allogeneic Stem Cell Transplantation (AlloSCT)

    ... study is to learn if giving donor lymphocyte cells and SGI-110 will help control AML and MDS. The safety of this treatment ... by vein over about 10-30 minutes. Other Names: DLI Stem cell transplantation AlloSCT ...

    Clinical Trial last updated 04/29/2016 - 12:20pm.

  6. Abatacept Reduced Intensity for Non-Malignant Diseases (Aba NMD)

    ... Purpose:  Allogeneic hematopoietic stem cell transplantation (HSCT) represents the only viable cure for children ... from graft versus host disease (GVHD), driven by donor T cells recognizing and reacting against disparate host antigens. This trial is ...

    Clinical Trial last updated 04/27/2016 - 2:40pm.

  7. Allo HSCT Using RIC for Hematological Diseases

    ... regimen followed by a related or unrelated donor stem cell infusion. The primary objective is to evaluate rates of acute ... Mycophenolate Mofetil Biological: Peripheral Blood Stem Cells On day 0, patients will receive an allogeneic transplant using PBSC ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  8. Sapacitibine shows promise for high-risk MDS patients

    ... factors, to intensive therapy with allogeneic hematopoietic stem cell transplantation (HSCT). Treatment selection should be based on the ... can help decrease the growth of abnormal bone marrow cells and  restore gene expression.  Failure of the hypomethylating agents, ...

    Research Review last updated 05/02/2016 - 9:30am.

  9. Immunosuppressive Therapy

    ... may prevent the bone marrow from making normal blood cells. Immunosuppressive therapy uses medicines to keep the immune system from ... are turned off by the cyclosporine, they stop attacking stem cells in the bone marrow. Then the stem cells may be able to ...

    Page last updated 01/20/2015 - 4:45pm.

  10. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... can be obtained in allogeneic blood or bone marrow stem cell transplantation using an human leukocyte antigen ( HLA ... (ATG) Procedure: Adipose derived mesenchymal stem cells ( AD-MSCs) Procedure: AD-MSC transdifferentiated HSCs (AD-HSCs) ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.