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  1. Detection of Recurrent Mutations by Pooled Targeted Next-Generation Sequencing in MDS Patients Prior to Treatment with Hypomethylating Agents or Stem Cell Transplantation

    ... and decitabine. The 76 patients in Cohort 2 underwent a stem cell transplant . The researchers focused on 74 genes, including ... , U2AF1 , SRSF2 , or ZRSR2 ). These genes help cells splice together certain DNA sequences as part of the protein-formation ...

    Research Review last updated 05/02/2016 - 9:26am.

  2. Gene Therapy for Fanconi Anemia

    ... efficiency for human FA patient hematopoietic progenitor cells transduced with a clinical grade lentiviral vector encoding the gene for ... Patients undergo bone marrow harvest for collection of stem/progenitor cells on day -1. REINFUSION: Patients undergo reinfusion of ...

    Clinical Trial last updated 04/28/2016 - 9:03am.

  3. MDS 101: Understanding Diagnosis and Treatment

    ... does not work well and fails to make enough healthy blood cells. People diagnosed with MDS can have low numbers of red blood cells, white ... approved specifically to treat MDS, such as chemotherapies, stem cell transplantation, and supportive care therapies like blood ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  4. MDS 101: Understanding Diagnosis and Treatment

    ... does not work well and fails to make enough healthy blood cells. People diagnosed with MDS can have low numbers of red blood cells, white ... approved specifically to treat MDS, such as chemotherapies, stem cell transplantation, and supportive care therapies like blood ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  5. Know Your Treatment Options

    ... A bone marrow transplant (BMT) is also called a stem cell transplant (SCT) or hematopoietic stem cell transplant (HSCT).The procedure replaces unhealthy blood-forming stem cells with healthy ones and offers some patients the possibility of a cure. But ...

    Topic section last updated 03/29/2016 - 9:04pm.

  6. 2014 Bone Marrow Failure Disease Symposia - Penn State College of Medicine

    ... with Umbilical Cord Blood and Haploidentical Stem Cells : A new and effective Treatment option for patients with ... Witold B. Rybka, MD, Professor and Director, Stem Cell Transplant Program Penn State Hershey Cancer Institute, ...

    Page last updated 10/29/2014 - 3:39pm.

  7. Clinical Trials Report for April 2014

    ... treated with drugs that suppress the immune system or with stem cell transplant. People with SAA who receive these treatments are more ... Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells ...

    Page last updated 04/18/2014 - 3:36pm.

  8. Aplastic Anemia 101: Understanding Diagnosis and Treatment

    ... happens when the bone marrow stops making enough red blood cells, white blood cells and platelets for the body. Aplastic anemia ... common treatments such as immunosuppressive drug therapy, stem cell transplantation, and supportive therapies like blood transfusions. He ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  9. Aplastic Anemia 101: Understanding Diagnosis and Treatment

    ... happens when the bone marrow stops making enough red blood cells, white blood cells and platelets for the body. Aplastic anemia can be ... treatments such as immunosuppressive drug therapy , stem cell transplantation, and supportive therapies like blood transfusions. He ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  10. PNH: Treatments

    ... can make it hard for your bone marrow to make red blood cells. So, unless you are receiving regular red blood cell transfusions, you ... next step. In this procedure, healthy bone marrow stem cells and other bone marrow cells are taken from a donor. These cells ...

    Page last updated 01/20/2015 - 4:48pm.