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  1. PNH 101: Understanding Diagnosis and Treatment

    ... a bone marrow failure disease that causes red blood cells to break apart. Doctors call this process hemolysis . This occurs ... eculizumab , immunosuppressive drug therapy , stem cell transplantation, and supportive therapies like blood transfusions. ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  2. PNH 101: Understanding Diagnosis and Treatment

    ... a bone marrow failure disease that causes red blood cells to break apart. Doctors call this process hemolysis . This occurs ... eculizumab , immunosuppressive drug therapy, stem cell transplantation, and supportive therapies like blood transfusions. ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  3. Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant

    ... side effects and best dose of selinexor when given after stem cell transplant in treating patients with acute myeloid leukemia that ... cancer growth by blocking an enzyme, which may cause cancer cells to die and also kill cells that cause the cancer to grow, which commonly ...

    Clinical Trial last updated 04/29/2016 - 10:38am.

  4. MDS 101: Understanding Diagnosis and Treatment

    ... does not work well and fails to make enough healthy blood cells. People diagnosed with MDS can have low numbers of red blood cells, white ... approved specifically to treat MDS, such as chemotherapies, stem cell transplantation, and supportive care therapies like blood ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  5. MDS 101: Understanding Diagnosis and Treatment

    ... does not work well and fails to make enough healthy blood cells. People diagnosed with MDS can have low numbers of red blood cells, white ... approved specifically to treat MDS, such as chemotherapies, stem cell transplantation, and supportive care therapies like blood ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  6. Detection of Recurrent Mutations by Pooled Targeted Next-Generation Sequencing in MDS Patients Prior to Treatment with Hypomethylating Agents or Stem Cell Transplantation

    ... and decitabine. The 76 patients in Cohort 2 underwent a stem cell transplant . The researchers focused on 74 genes, including ... , U2AF1 , SRSF2 , or ZRSR2 ). These genes help cells splice together certain DNA sequences as part of the protein-formation ...

    Research Review last updated 05/02/2016 - 9:26am.

  7. Hideki Makishima, MD, PhD

    ... mutation in the gene called PIG-A is acquired in the stem cells (mother cells of all blood cells) in the bone marrow of ...

    Grant Recipient last updated 07/07/2014 - 11:46am.

  8. Aplastic Anemia 101: Understanding Diagnosis and Treatment

    ... happens when the bone marrow stops making enough red blood cells, white blood cells and platelets for the body. Aplastic anemia ... common treatments such as immunosuppressive drug therapy, stem cell transplantation, and supportive therapies like blood transfusions. He ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  9. Aplastic Anemia 101: Understanding Diagnosis and Treatment

    ... happens when the bone marrow stops making enough red blood cells, white blood cells and platelets for the body. Aplastic anemia can be ... treatments such as immunosuppressive drug therapy , stem cell transplantation, and supportive therapies like blood transfusions. He ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  10. Gene Therapy for Fanconi Anemia

    ... efficiency for human FA patient hematopoietic progenitor cells transduced with a clinical grade lentiviral vector encoding the gene for ... Patients undergo bone marrow harvest for collection of stem/progenitor cells on day -1. REINFUSION: Patients undergo reinfusion of ...

    Clinical Trial last updated 04/28/2016 - 9:03am.