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  1. What are the treatments for PNH?

    ... This reduces hemolysis , the destruction of red blood cells. Bone marrow/stem cell transplantation (BMT/SCT):  A procedure that replace your unhealthy ...

    FAQ last updated 03/15/2016 - 11:32pm.

  2. PNH: Treatments

    ... can make it hard for your bone marrow to make red blood cells. So, unless you are receiving regular red blood cell transfusions, you ... next step. In this procedure, healthy bone marrow stem cells and other bone marrow cells are taken from a donor. These cells ...

    Page last updated 01/20/2015 - 4:48pm.

  3. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... post-transplant with MLN9708 to both sensitize tumor cells to NK cytotoxicity and protect against graft-versus-host disease ... reconstitution following haploidentical peripheral blood stem cell transplantation. Patients will receive a nonmyeloablative ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  4. GVAX vs. Placebo for MDS/AML After Allo HSCT

    ... your MDS or AML from relapsing after your allogeneic stem cell transplantation. "Investigational" means that the vaccine is still ... treatment for MDS/AML. It can be effective because the cells from your donor (also known as the graft) could form a new immune system ...

    Clinical Trial last updated 04/28/2016 - 12:01pm.

  5. Cristian Bellodi, PhD

    ... Emerging role of p53 translation control in hematopoietic stem cell quiescence and differentiation ... the original research proposal that were directly applied to cells isolated from patients with bone marrow failure . In addition, ...

    Grant Recipient last updated 12/10/2012 - 10:40am.

  6. Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

    ... given together with chemotherapy before donor stem cell transplant in treating patients with myelodysplasticsyndrome or ... as total marrow and lymphoid irradiation, to kill cancer cells, but these treatment kills normal cells as well. After chemotherapy, ...

    Clinical Trial last updated 04/29/2016 - 12:58pm.

  7. Aplastic Anemia Clinical Trial at the NIH

    ... may also cause the body to make more red and white blood cells. In a trial performed at the NIH where patients with severe aplastic ... suggest that eltrombopag may stimulate hematopoietic stem cells , not just the cells that make platelets, which is a very ...

    Research Review last updated 05/02/2016 - 9:26am.

  8. Related Diseases

    ... cancer that occurs when young abnormal white blood cells (leukemia cells) start to fill up the bone marrow and interfere with the ... versus host disease (GVHD) is a common complication of a stem cell/ bone marrow transplant . It happens when the donor's immune ...

    Page last updated 07/07/2016 - 3:16pm.

  9. Acute Myeloid Leukemia (AML)

    ... a blood cancer. It happens when young abnormal white blood cells called blasts (leukemia cells), begin to fill up the bone ... an anthracycline (such as daunorubicin or idarubicin). Stem cell transplantation may be used after chemotherapy as a second phase of ...

    Topic section last updated 07/07/2016 - 3:15pm.

  10. T-cell Depleted Alternative Donor Transplantation

    ... disease (GVHD) in patients receiving a stem cell transplant from an alternative (unrelated and mismatched related) ... and post-transplant infections. Patients requiring stem cell transplants for either malignant (cancerous) or non-malignant disease ... Device: CliniMACS® (T cell depletion) Stem cells will be collected from donors after they receive Granulocyte ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.