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  1. Paroxysmal Nocturnal Hemoglobinuria (PNH)

    ... ( PNH ) is a rare blood disease that causes red blood cells to break apart. Doctors call this breaking apart " hemolysis ." It ... inside certain bones. Marrow contains blood-forming stem cells that make copies of themselves to create all 3 types of blood ...

    Page last updated 09/30/2017 - 11:34am.

  2. Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia

    ... 13, 2016 Memory stem T cells (TSCMs) constitute a long-lived, self-renewing lymphocyte ...

    Research Article last updated 04/29/2016 - 12:59pm.

  3. Standardized High-Sensitivity Flow Cytometry Testing for Paroxysmal Nocturnal Hemoglobinuria in Children with Acquired Bone Marrow Failure Disorders: A Single Center U.S. Study

    ... hemoglobinuria (PNH) is a rare, acquired hematopoietic stem cell disorder that has not been well documented in children, particularly ... 1% PNH population) and 10 had minor PNH population or rare cells with PNH phenotype (≤ 1% PNH population). CONCLUSIONS: This is ...

    Research Article last updated 06/26/2017 - 9:22am.

  4. MDS expert finds promising antibody

    ... Researchers find new way to target blood stem cell cancers Article Source:  ... CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) ...

    Article last updated 01/26/2017 - 1:14pm.

  5. Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes

    ... or constitutively activated in bone marrow hematopoietic stem and progenitor cells. Mounting experimental results indicate that the dysregulation of these ...

    Research Article last updated 06/21/2017 - 11:10am.

  6. Stem and progenitor cell alterations in myelodysplastic syndromes

    ... a small population of disease initiating hematopoietic stem cells (HSCs) that persist and expand through conventional therapies and are ...

    Research Article last updated 02/21/2017 - 10:17am.

  7. Advances in antiviral drug cuts infection post SCT

    ... infection and improves survival in patients undergoing donor stem cell transplant Article Source:  ... CMV infection following transplant with donor stem cells . The patients, who were undergoing transplant as treatment for ...

    Article last updated 02/23/2017 - 7:26am.

  8. Study of aplastic anemia med shows significant results

    ... therapies are effective, but reduced numbers of residual stem cells may limit their efficacy. In patients with aplastic anemia that was ...

    Article last updated 04/24/2017 - 7:14am.

  9. Clinical applications of haploidentical hematopoietic stem cell transplantation in severe aplastic anemia

    ... efficacy and safety of haploidentical allogeneic hemopoietic stem cell transplantation (allo-HSCT) in severe aplastic anemia (SAA) ... with the parents as the donors of hemopoietic stem cells . The conditioning regimen before HSCT included cyclophosphamide ...

    Research Article last updated 02/03/2017 - 9:36am.

  10. Overcoming age barrier to transplantation

    ... leukemia. Many have benefited from advances in hematopoietic stem cell transplants that can cure these and other diseases. These transplants often depend on others for a source of cells. Since a minority of patients have a matched sibling donor, success often ...

    Article last updated 04/03/2017 - 2:00pm.