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  1. Study of aplastic anemia med shows significant results

    ... therapies are effective, but reduced numbers of residual stem cells may limit their efficacy. In patients with aplastic anemia that was ...

    Article last updated 04/24/2017 - 7:14am.

  2. Stem and progenitor cell alterations in myelodysplastic syndromes

    ... a small population of disease initiating hematopoietic stem cells (HSCs) that persist and expand through conventional therapies and are ...

    Research Article last updated 02/21/2017 - 10:17am.

  3. Advances in antiviral drug cuts infection post SCT

    ... infection and improves survival in patients undergoing donor stem cell transplant Article Source:  ... CMV infection following transplant with donor stem cells . The patients, who were undergoing transplant as treatment for ...

    Article last updated 02/23/2017 - 7:26am.

  4. Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia

    ... 13, 2016 Memory stem T cells (TSCMs) constitute a long-lived, self-renewing lymphocyte ...

    Research Article last updated 04/29/2016 - 12:59pm.

  5. Clinical applications of haploidentical hematopoietic stem cell transplantation in severe aplastic anemia

    ... efficacy and safety of haploidentical allogeneic hemopoietic stem cell transplantation (allo-HSCT) in severe aplastic anemia (SAA) ... with the parents as the donors of hemopoietic stem cells . The conditioning regimen before HSCT included cyclophosphamide ...

    Research Article last updated 02/03/2017 - 9:36am.

  6. A retrospective study of paroxysmal nocturnal hemoglobinuria in pediatric and adolescent patients

    Journal Title:  Blood Cells Mol Dis Primary Author:  ... whereas four patients with PNH/BMD underwent hematopoietic stem cell transplantation. Our series confirm that the most frequent ...

    Research Article last updated 05/02/2017 - 10:42am.

  7. Updates on the pathophysiology and treatment of aplastic anemia: a comprehensive review.

    ... commentary: Immune-mediated destruction of hematopoietic stem and progenitor cells, leading to a marrow devoid of hematopoietic elements, and peripheral ...

    Research Article last updated 05/02/2017 - 10:13am.

  8. Overcoming age barrier to transplantation

    ... leukemia. Many have benefited from advances in hematopoietic stem cell transplants that can cure these and other diseases. These transplants often depend on others for a source of cells. Since a minority of patients have a matched sibling donor, success often ...

    Article last updated 04/03/2017 - 2:00pm.

  9. New positive results for GVHD treatment

    ... treat a common and serious complication of a type of stem cell transplant , findings from a small clinical trial show. ... after receiving a transplant of donated blood stem cells , known as an allogeneic transplant. The patients’ ...

    Article last updated 01/12/2017 - 11:10am.

  10. Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

    ... which involves active destruction of hematopoietic stem cells and progenitors by cytotoxic T cells in the bone marrow. Aberrant ...

    Research Article last updated 01/24/2017 - 10:08am.