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  1. Anti-Complement Treatment in Paroxysmal Nocturnal Hemoglobinuria: Where we Stand and Where we are Going

    ... disorder characterized by the expansion of hematopoietic stem cells and progeny mature blood cells which are deficient in some surface ...

    Research Article last updated 05/22/2014 - 8:24am.

  2. Recent developments in bone marrow transplants

    ... Celgene) maintenance following autologous hematopoietic stem cell transplantation improved survival outcomes without increasing the ... donor . Repeated infusions of mesenchymal stromal cells reduced the incidence of chronic GVHD in patients who underwent ...

    Article last updated 11/16/2016 - 2:56pm.

  3. Pathogenesis of MDS: An Overview of molecular and non-molecular aspects of the disease

    ... a group of clonal disorders arising from hematopoietic stem cells generally characterized by inefficient hematopoiesis , ...

    Research Article last updated 05/12/2015 - 9:47am.

  4. Interviews with the Experts Transplantation & GVHD: What Patients Need to Know

    Why is stem cell transplantation considered a treatment option for many aplastic anemia , MDS or PNH patients? Hematopoietic stem cell transplantation (HSCT) involves the intravenous or IV (injected into a vein) infusion of stem cells to reestablish hematopoietic (blood forming) function in patients ...

    Interview last updated 09/30/2014 - 11:07am.

  5. An update on the treatment of myelodysplastic syndromes.

    ... heterogeneous clonal disorders of myeloid hematopoietic stem cells affecting about 300,000 people worldwide. Ineffective ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. MicroRNAs in the pathogenesis of myelodysplastic syndromes and myeloid leukaemia

    ... in self-renewal and transformation of haematopoietic stem cells , as well as their ability to induce epigenetic alterations in the ...

    Research Article last updated 06/02/2014 - 10:35am.

  7. Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disorders

    ... disorder characterized by the expansion of hematopoietic stem cells and progeny mature blood cells which are deficient in some surface ...

    Research Article last updated 10/02/2012 - 10:00am.

  8. Allogeneic BM transplantation for the treatment of aplastic anemia: current results and expanding donor possibilities

    ... or from an unrelated one, the use of peripheral blood stem cells must be strongly discouraged because they have been systematically ...

    Research Article last updated 01/07/2014 - 12:31pm.

  9. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... and basiliximab for GVHD prophylaxis. Mesenchymal stem cells derived from unrelated umbilical cord were infused on day 1. ...

    Research Article last updated 09/04/2014 - 11:22am.

  10. SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes.

    ... In aplastic anemia (AA), contraction of the stem cell pool may result in oligoclonality while in myelodysplastic ... aberrations expands and outcompetes normal stem cells . We analyzed patients with AA (N=93) and hypocellular MDS ...

    Research Article last updated 10/11/2011 - 5:58pm.