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  1. Hematopoietic stem cell transplantation for older patients with myelodysplastic syndromes.

    ... is primarily a disease of older age, and hematopoietic cell transplantation is the only treatment modality that offers the potential ... decade of life have been transplanted successfully. However, transplant outcome strongly depends on the disease characteristics and comorbid ...

    Research Article last updated 10/30/2013 - 8:59am.

  2. Hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: long-term results of a retrospective study on behalf of the Gruppo Italiano Trapianto Midollo Osseo (GITMO).

    ... is an acquired clonal disorder of the hemopoietic stem cells for which the only curative treatment is allogeneic hematopoietic stem cell transplantation. DESIGN AND METHODS: The aim of this ... failure was 8% (4% primary and 4% secondary graft failure). Transplant-related mortality for all patients was 42% (26% and 63% for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Myelodysplastic syndrome hematopoietic stem cell

    ... syndromes (MDSs) are clonal hematopoietic stem cell (HSC) malignancies that are characterized by ineffective hematopoiesis ... probably because of the improvement of bone marrow transplant procedures. The lack of other options underscores the urgent ...

    Research Article last updated 11/05/2012 - 10:21am.

  4. Optimizing stem cell transplantation in myelodysplastic syndromes: unresolved questions.

    ... PURPOSE OF REVIEW: Allogeneic hematopoietic stem cell transplantation (HCT) is the only curative therapy for myelodysplastic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.

    ... immune-mediated functional impairment of hematopoietic stem cells . Transplantation of these cells is a first-line treatment option ... were identified as factors for improved survival in the transplant group. Advanced age, SAA without very severe aplastic anemia, and ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Myelodysplastic syndrome evolving from aplastic anemia treated with immunosuppressive therapy: efficacy of hematopoietic stem cell transplantation.

    ... syndrome). Many will proceed to allogeneic hematopoietic stem cell transplantation. We identified 123 patients with post-aplastic anemia ...

    Research Article last updated 08/21/2014 - 9:32am.

  7. Jill Whitney – Since my diagnosis, my mission has been to fight back

    ... regimen for transplant, and on May 25th, I received the stem cells of my 47-year old German donor. I encountered a few setbacks ... 25, 2015, I celebrated the fifth anniversary of my stem cell transplant (re-birthday). I tolerate chemotherapy pretty well now and ...

    Patient Chronicle last updated 05/26/2015 - 9:29am.

  8. ALLOGENEIC STEM CELL TRANSPLANTATION (HSCT) FOR ADULTS WITH MYELODYSPLASTIC SYNDROMES (MDS): RELEVANCE OF PRE-TRANSPLANT DISEASE STATUS.

    ... with myelodysplasia (MDS) who received an allogeneic stem cell transplantation between January 1995 and September 2010 in two Italian ...

    Research Article last updated 06/28/2013 - 1:28pm.

  9. Hematopoietic stem cell transplantation in children and young adults with secondary myelodysplastic syndrome and acute myeloid leukemia following aplastic anemia

    ... anemia . Here we evaluate the outcome of hematopoietic stem cell transplantation (HSCT) in 17 children and young adults with sMDS/sAML ...

    Research Article last updated 01/07/2014 - 12:37pm.

  10. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... (OS) separately in the 2 arms at 1 year post-hematopoietic stem cell transplantation (HSCT). Status:  ...

    Clinical Trial last updated 05/22/2017 - 11:00am.