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  1. CASCADE (SGN33A-005)

    ... t(15;17) Patients who are candidates for allogeneic stem cell transplant at the time of enrollment Patients with a history of ...

    Clinical Trial last updated 06/19/2017 - 2:43pm.

  2. NHLBI profiles a member of the Foundation’s patient community.

    ... have no apparent origin. Emily first found out her blood cell counts were abnormally low when she was being treated for rheumatoid ... therapy. The hope: that the treatment would allow the stem cells in her bone marrow to grow and produce normal blood cell levels. ...

    Article last updated 06/13/2016 - 1:51pm.

  3. Personalized medicine for MDS

    ... for a more intensive treatment, such as allogeneic stem cell transplant , earlier in the course of disease.  This personalized ...

    Research Review last updated 05/02/2016 - 9:44am.

  4. Myelodysplastic syndromes: Contemporary review and how we treat

    ... syndromes (MDS) are a heterogeneous group of clonal stem cell disorders with an inherent tendency for leukemic transformation. Diagnosis ...

    Research Article last updated 04/29/2016 - 1:05pm.

  5. Allogeneic stem cell transplantation using alemtuzumab-containing regimens in severe aplastic anemia.

    ... aid engraftment after allogeneic haemopoietic stem cell transplant (HSCT). Its associated low incidence of GVHD makes it an ...

    Research Article last updated 06/20/2013 - 10:30am.

  6. Allogeneic haematopoietic stem cell transplantation in myelodysplastic syndromes

    ... PURPOSE OF REVIEW: Allogeneic haematopoietic stem cell transplantation remains the only curative treatment for myelodysplastic ...

    Research Article last updated 09/24/2014 - 10:46am.

  7. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... of combined haploidentical hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC) affected graft failure ... received haploidentical HSCT plus MSC infusion. Stem cell grafts used a combination of granulocyte colony-stimulating ... (500 mg/m2·d)+anti-human thymocyte IgG. Transplant recipients also received cyclosporin A, mycophenolatemofetil, and ...

    Research Article last updated 04/09/2014 - 9:16am.

  8. Matched sibling donor hematopoietic stem cell transplant in patients with acquired aplastic anemia

    ... in the definitive treatment forms available, hematopoietic stem cell transplantation (HSCT) [1] and immunosuppressive treatment (IS) have also ...

    Research Article last updated 01/20/2015 - 2:33pm.

  9. Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis

    ... of IST. Likely, in the future, further improvements in the transplant setting, will continue to move up the role of HSCT in the treatment ...

    Research Article last updated 03/03/2015 - 11:27am.

  10. Non-myeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia

    ... report our pilot findings with haploidentical hematopoietic stem cell transplantation (haploHSCT) using uniform reduced-intensity conditioning ...

    Research Article last updated 08/04/2014 - 8:20am.