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  1. New data presented at ASCO on secondary MDS/AML

    ... in Breast and Ovarian Cancer Patients Cause AML and MDS? Article Source:  ... Cancer patients with secondary malignancies have limited access to data regarding the possibility of ...

    Article last updated 06/05/2017 - 9:37am.

  2. Foundation Update - June 2016

    ... aplastic anemia , myelodysplastic syndromes (MDS), and paroxysmal nocturnal hemoglobinuria (PNH). The two-year ... June 14, 2016, 1:00 PM EDT •  PNH:Secondary Mutations and Thrombosis; June 21, 2016, 1:00 PM EDT ...

    Article last updated 10/09/2017 - 2:54pm.

  3. Response to azacitidine is independent of p53 expression in higher-risk myelodysplastic syndromes and secondary acute myeloid leukemia.

    ... Higher-risk myelodysplastic syndromes (MDS) frequently progress to secondary AML (sAML) within months even in the presence of continuous therapy ...

    Research Article last updated 07/07/2014 - 9:27am.

  4. Somatic HLA mutations expose the role of class I–mediated autoimmunity in aplastic anemia and its clonal complications

    ... and a predisposition to myelodysplastic syndrome (MDS) and leukemia. Although its exact pathogenesis is unknown, aAA is thought ... and metaphase cytogenetics , and more frequent secondary MDS . The finding of recurrent HLA class I mutations provides ...

    Research Article last updated 10/23/2017 - 10:56am.

  5. Foundation Update - May 2016

    ... ; May 18, 1:00 PM EDT • What is Secondary MDS? Everything You Need to Know ;May 26, 2016, 1:00 PM EDT ... Understanding and Managing Iron Overload in MDS ; June 10, 2016, 1:00 PM EDT   Conferences ...

    Article last updated 10/09/2017 - 2:55pm.

  6. Foundation Update - November 2016

    ... about clinical trial design and the state of current MDS research. PACCT+ is a two-year demonstration project to develop and test a ... Some patients with MDS may progress to Secondary Acute Myeloid Leukemia (Secondary AML), a type of blood and bone ...

    Article last updated 10/09/2017 - 2:48pm.

  7. Causes

    ... De Novo MDS The cause of most MDS cases is ... call this: Therapy-related MDS Secondary MDS On average, treatment-related MDS happens 5 to 7 years ...

    Topic section last updated 04/06/2018 - 12:27pm.

  8. A Phase II Study of SGI-110 in Philadelphia-Negative Myeloproliferative Neoplasms

    ... Neoplasms (MPN) (excluding PV, ET and primary/secondary myelofibrosis).  The study will enroll approximately 50 patients at ... Leukemia (aCML), Chronic Myelomonocytic Leukemia (CMML), MPN/MDS overlap syndromes, accelerated phase myelofibrosis and MPN unclassifiable. ...

    Clinical Trial last updated 05/14/2018 - 2:02pm.

  9. SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias

    ... myelodysplastic syndromes (MDS) ...

    Research Article last updated 03/05/2013 - 9:00am.

  10. Factors affecting response to treatment for secondary MDS and AML

    ... to access the full report. Abstract # 6603 Secondary or t-MDS It is important to recognize that, while secondary MDS (t-MDS) ...

    Research Review last updated 05/02/2016 - 9:32am.