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  1. REVERSE 1 INCB 18424-271

    ... With Corticosteroids for the Treatment of Steroid- Refractory Acute Graft-Versus-Host Disease - The purpose of this study is ... corticosteroids in subjects with Grades II to IV steroid-refractory acute graft-versus-host disease (GVHD) . ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  2. Pediatric myelodysplastic syndromes: they do exist!

    ... hypocellular bone marrow and monosomy 7 . Refractory cytopenia is more typical than refractory anemia , as seen in the elderly. Its recognition and ...

    Research Article last updated 01/08/2014 - 9:02am.

  3. Distinct iron architecture in SF3B1 mutant myelodysplastic syndromes patients is linked to an SLC25A37 splice variant with a retained intron

    ... ring sideroblasts (RS). RS is a cardinal feature of refractory anemia with RS (RARS) and RARS with marked ...

    Research Article last updated 06/02/2014 - 10:42am.

  4. The Myelodysplastic Syndromes (MDS): A personal recollection of four decades of classification and prognostic scoring systems.

    ... with myelodysplastic syndromes (MDS), namely refractory anemia with excess blasts (RAEB) and chronic ...

    Research Article last updated 05/14/2013 - 2:59pm.

  5. 5-Azacitidine efficacy and safety in patients aged >65 years with myelodysplastic syndromes outside clinical trials

    ... 5+2 +2): seven patients were classified as having refractory cytopenia with multilineage dysplasia (RCMD), nine patients with refractory anemia with excess of blasts (RAEB) type 1, 18 ...

    Research Article last updated 06/15/2012 - 2:13pm.

  6. High-dose cyclophosphamide for severe aplastic anemia: long-term follow-up.

    ... follow-up on 67 SAA patients (44 treatment-naive and 23 refractory ) treated with high-dose cyclophosphamide. At 10 years, the ... was 58% in 44 treatment-naive SAA patients. Patients with refractory SAA fared less well after high-dose cyclophosphamide therapy; at 10 ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Tea consumption reduces the risk of de novo myelodysplastic syndromes

    ... The inverse association existed in both genders, in the refractory anemia with excessive blasts subtype, in ... System lower and higher risk groups, but not in the refractory cytopenia with multilineage dysplasia subtype. The study ...

    Research Article last updated 01/20/2015 - 12:56pm.

  8. ALLOGENEIC STEM CELL TRANSPLANTATION (HSCT) FOR ADULTS WITH MYELODYSPLASTIC SYNDROMES (MDS): RELEVANCE OF PRE-TRANSPLANT DISEASE STATUS.

    ... the time of transplant, 53 patients (56%) had relapsed/ refractory disease. The cumulative incidence of grades II-IV acute ...

    Research Article last updated 06/28/2013 - 1:28pm.

  9. Eltrombopag in aplastic anemia

    ... treatment of patients with severe aplastic anemia (SAA) refractory to IST. There is evidence that this drug works by directly ... combination therapy in the upfront treatment of SAA, in IST-refractory SAA and in moderate disease. Bone ...

    Research Article last updated 03/02/2015 - 12:51pm.

  10. The impact of hypomethylating agents on the cost of care and survival of elderly patients with myelodysplastic syndromes

    ... 24-month survival (especially among patients with refractory anemia or refractory anemia with excess blasts ). The magnitude of the cost of ...

    Research Article last updated 10/01/2012 - 9:41am.