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  1. A Study of BBI608 in Adult Patients With Advanced, Refractory Hematologic Malignancies

    ... study of BBI608 administered to patients with relapsed, refractory hematologic malignancies, including multiple myeloma, lymphoma, ...

    Clinical Trial last updated 04/28/2016 - 3:34pm.

  2. Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

    ... CPI-613 is effective and safe in either patients with refractory or relapsed acute myeloid leukemia (AML) or patients ...

    Clinical Trial last updated 04/28/2016 - 12:21pm.

  3. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... failure. People with aplastic anemia who have refractory disease (not responding to standard treatment) may join. ...

    Clinical Trial last updated 04/21/2016 - 1:19pm.

  4. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... However, we are designing a new trial for patients with refractory aplastic anemia that includes children. We also currently have a ... untreated moderate aplastic anemia in adults, another for refractory aplastic anemia in adults (an extension of the published study), and ...

    Interview last updated 07/06/2012 - 3:42pm.

  5. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... lacking suitable identical donors and those who are refractory to immunosuppressive therapy (IST). The current study evaluated ...

    Research Article last updated 02/03/2017 - 9:40am.

  6. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... one trial of immunosuppressive therapy (IST) by being refractory or having relapsed. IST could have included ATG based regimens, ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  7. Eltrombopag for the treatment of aplastic anemia: current perspectives

    ... patients. A significant proportion of patients are refractory to IST or relapse after IST. Various strategies have been ... as an encouraging and promising agent for patients with refractory AA. It has demonstrated efficacy in restoring trilineage ...

    Research Article last updated 11/01/2016 - 2:01pm.

  8. Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

    ... restricted to select patients. New strategies for ESA- refractory or relapsed patients include lenalidomide , alone or in ...

    Research Article last updated 12/09/2016 - 2:50pm.

  9. Left main crossover stenting in a patient with severe thrombocytopenia due to aplastic anemia

    ... 11 × 103/μL, hemoglobin 6.4 g/dL). Refractory heart failure persisted despite repeated conservative ...

    Research Article last updated 12/09/2016 - 2:08pm.

  10. Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia

    ... This result suggests that both newly diagnosed and refractory pediatric SAA patients benefit from haplo-HSCT, especially when ...

    Research Article last updated 01/24/2017 - 11:52am.