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  1. Study of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

    ... the use of IRX5183 in 1) patients with relapsed and/or refractory AML and 2) patients with high-risk MDS or chronic myelomonocytic ...

    Clinical Trial last updated 04/29/2016 - 10:22am.

  2. ONC201 in Relapsed/Refractory Acute Leukemias and High-risk Myelodysplastic Syndromes (HR-MDS)

    ... of ONC201 that can be given to patients with relapsed or refractory AML, ALL, or MDS. The goal of Phase II of this study is to ...

    Clinical Trial last updated 04/29/2016 - 10:14am.

  3. A Study of BBI608 in Adult Patients With Advanced, Refractory Hematologic Malignancies

    ... study of BBI608 administered to patients with relapsed, refractory hematologic malignancies, including multiple myeloma, lymphoma, ...

    Clinical Trial last updated 04/28/2016 - 3:34pm.

  4. Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

    ... CPI-613 is effective and safe in either patients with refractory or relapsed acute myeloid leukemia (AML) or patients ...

    Clinical Trial last updated 04/28/2016 - 12:21pm.

  5. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... failure. People with aplastic anemia who have refractory disease (not responding to standard treatment) may join. ...

    Clinical Trial last updated 04/21/2016 - 1:19pm.

  6. A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients with Myelodysplastic Syndrome (MDS)

    ... cell transplantation. For patients in the relapse or refractory cohort, any other therapy not being a hypomethylating agent ...

    Clinical Trial last updated 05/14/2018 - 1:57pm.

  7. HYPOMETHYLATING AGENTS (HMA) TREATMENT FOR MYELODYSPLASTIC SYNDROMES: ALTERNATIVES IN THE FRONTLINE AND RELAPSE SETTINGS

    ... an increasing focus on studying treatments for patients refractory to HMA treatment. ...

    Research Article last updated 07/18/2017 - 1:15pm.

  8. Study of aplastic anemia med shows significant results

    ... efficacy. In patients with aplastic anemia that was refractory to immunosuppression, eltrombopag, a synthetic ...

    Article last updated 04/24/2017 - 7:14am.

  9. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... lacking suitable identical donors and those who are refractory to immunosuppressive therapy (IST). The current study evaluated ...

    Research Article last updated 02/03/2017 - 9:40am.

  10. Eltrombopag for the treatment of aplastic anemia: current perspectives

    ... patients. A significant proportion of patients are refractory to IST or relapse after IST. Various strategies have been ... as an encouraging and promising agent for patients with refractory AA. It has demonstrated efficacy in restoring trilineage ...

    Research Article last updated 11/01/2016 - 2:01pm.