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  1. Clinical Outcomes in Adult Patients with Aplastic Anemia- a single institution experience

    ... IST regimens in frontline and relapsed/ refractory (R/R) settings. Pretreatment and on-treatment clinical ... prior response to ATG: prior responders (46%) vs primary refractory (0%) (p<0.01). In the R/R setting, there was no survival difference ...

    Research Article last updated 09/13/2017 - 7:40am.

  2. Patient Trusts Her Instincts in Finding the Right Treatment

    ... MDS (myelodysplastic syndrome). Specifically, it was the Refractory Anemia with Ringed Sideroblasts, (RARS) subtype.  I was ...

    Patient Chronicle last updated 05/10/2018 - 11:01am.

  3. Early treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion independence

    ... by ineffective hematopoiesis resulting in refractory cytopenias. Red blood cell (RBC) transfusions can ...

    Research Article last updated 09/13/2017 - 8:58am.

  4. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... World Health Organization (WHO) criteria (Appendix 2) or refractory anemia with excess blasts in transformation (RAEB t) ...

    Clinical Trial last updated 05/04/2018 - 3:53pm.

  5. Retired MDS Patient Living Life to the Fullest Since Transplant

    ... thought was, "I can't even spell it!"  The stage was Refractory Anemia with Excess Blasts (RAEB-1) with one ...

    Patient Chronicle last updated 04/26/2018 - 10:43am.

  6. Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

    ... and cytarabine in pediatric patients with relapsed or refractory hematologic malignancies included acute myeloid leukemia (AML), ... with fludarabine and cytarabine in patients with relapsed or refractory hematologic malignancies ...

    Clinical Trial last updated 04/28/2016 - 9:48am.

  7. Promising news for older AML patients

    ... has shown good single-agent activity against relapsed/ refractory AML and, as reported in a phase 1b study at the 2016 annual ...

    Article last updated 07/19/2017 - 11:19am.

  8. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... Patients with relapsed or refractory SAA or very SAA defined: Bone marrow (< 25% ... Patients with inherited disease will be characterized as refractory and do not require immunosuppressive first. Age 0- upper ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  9. 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... (relapsed) or has not responded to previous treatment ( refractory ). Drugs used in chemotherapy , such as ...

    Clinical Trial last updated 05/23/2016 - 3:25pm.

  10. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... However, we are designing a new trial for patients with refractory aplastic anemia that includes children. We also currently have a ... untreated moderate aplastic anemia in adults, another for refractory aplastic anemia in adults (an extension of the published study), and ...

    Interview last updated 07/06/2012 - 3:42pm.