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  1. Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

    ... and cytarabine in pediatric patients with relapsed or refractory hematologic malignancies included acute myeloid leukemia (AML), ... with fludarabine and cytarabine in patients with relapsed or refractory hematologic malignancies ...

    Clinical Trial last updated 04/28/2016 - 9:48am.

  2. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... Patients with relapsed or refractory SAA or very SAA defined: Bone marrow (< 25% ... Patients with inherited disease will be characterized as refractory and do not require immunosuppressive first. Age 0- upper ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  3. 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... (relapsed) or has not responded to previous treatment ( refractory ). Drugs used in chemotherapy , such as ...

    Clinical Trial last updated 05/23/2016 - 3:25pm.

  4. Study of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

    ... the use of IRX5183 in 1) patients with relapsed and/or refractory AML and 2) patients with high-risk MDS or chronic myelomonocytic ...

    Clinical Trial last updated 04/29/2016 - 10:22am.

  5. ONC201 in Relapsed/Refractory Acute Leukemias and High-risk Myelodysplastic Syndromes (HR-MDS)

    ... of ONC201 that can be given to patients with relapsed or refractory AML, ALL, or MDS. The goal of Phase II of this study is to ...

    Clinical Trial last updated 04/29/2016 - 10:14am.

  6. A Study of BBI608 in Adult Patients With Advanced, Refractory Hematologic Malignancies

    ... study of BBI608 administered to patients with relapsed, refractory hematologic malignancies, including multiple myeloma, lymphoma, ...

    Clinical Trial last updated 04/28/2016 - 3:34pm.

  7. Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

    ... CPI-613 is effective and safe in either patients with refractory or relapsed acute myeloid leukemia (AML) or patients ...

    Clinical Trial last updated 04/28/2016 - 12:21pm.

  8. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... failure. People with aplastic anemia who have refractory disease (not responding to standard treatment) may join. ...

    Clinical Trial last updated 04/21/2016 - 1:19pm.

  9. Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia

    ... This result suggests that both newly diagnosed and refractory pediatric SAA patients benefit from haplo-HSCT, especially when ...

    Research Article last updated 01/24/2017 - 11:52am.

  10. Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

    ... restricted to select patients. New strategies for ESA- refractory or relapsed patients include lenalidomide , alone or in ...

    Research Article last updated 12/09/2016 - 2:50pm.