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  1. Increasing the effectiveness of hematopoiesis in myelodysplastic syndromes: erythropoiesis-stimulating agents and transforming growth factor-β superfamily inhibitors

    ... responses are often short-lived. In fact, many ESA- refractory patients harbor defects in late-stage erythropoiesis downstream ...

    Research Article last updated 10/23/2017 - 11:08am.

  2. Types

    ... in bone marrow RA ( Refractory Anemia ) < 1 < 5 RARS (Refractory Anemia with Ring Sideroblasts < 1 ...

    Topic section last updated 11/14/2016 - 1:11pm.

  3. Increasing the effectiveness of hematopoiesis in myelodysplastic syndromes: erythropoiesis-stimulating agents and transforming growth factor-β superfamily inhibitors

    ... responses are often short-lived. In fact, many ESA- refractory patients harbor defects in late-stage erythropoiesis downstream ...

    Research Article last updated 10/02/2017 - 10:10am.

  4. Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia

    ... therapy (IST) or IST and eltrombopag; 10 IST- refractory patients who had received eltrombopag only), focusing on ...

    Research Article last updated 10/02/2017 - 9:40am.

  5. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... children, adolescents and young adults with relapsed or refractory hematologic malignancies ... ALL, and must have disease that has relapsed or is refractory to chemotherapy , or that has relapsed after HSCT. ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.

  6. Clinical Outcomes in Adult Patients with Aplastic Anemia- a single institution experience

    ... IST regimens in frontline and relapsed/ refractory (R/R) settings. Pretreatment and on-treatment clinical ... prior response to ATG: prior responders (46%) vs primary refractory (0%) (p<0.01). In the R/R setting, there was no survival difference ...

    Research Article last updated 09/13/2017 - 7:40am.

  7. Early treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion independence

    ... by ineffective hematopoiesis resulting in refractory cytopenias. Red blood cell (RBC) transfusions can ...

    Research Article last updated 09/13/2017 - 8:58am.

  8. The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood - a prospective study by EWOG-MDS.

    Journal Title:  Leukemia Primary Author:  Aalbers AM Author(s):  Aalbers AM, ...

    Research Article last updated 07/29/2014 - 11:53am.

  9. Phase I trial of SAR103168, a novel multi-kinase inhibitor,in patients with refractory/relapsed acute leukemias or high-risk myelodysplastic syndromes

    Journal Title:  Leuk Lymphoma Primary Author:  Roboz GJ Author(s):  Roboz GJ,...

    Research Article last updated 05/22/2014 - 9:43am.

  10. Eltrombopag in refractory severe aplastic anemia

    Journal Title:  Blood Primary Author:  No authors listed Author(s):  No autho...

    Research Article last updated 04/16/2014 - 11:34am.