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  1. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... lacking suitable identical donors and those who are refractory to immunosuppressive therapy (IST). The current study evaluated ...

    Research Article last updated 02/03/2017 - 9:40am.

  2. Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia

    ... This result suggests that both newly diagnosed and refractory pediatric SAA patients benefit from haplo-HSCT, especially when ...

    Research Article last updated 01/24/2017 - 11:52am.

  3. Good riddance to the term "refractory anemia" in myelodysplastic syndromes

    ... The term " refractory anemia " was used in 1937 by Cornelius Parker Rhoads to ... the World Health Organization (WHO) proposed elimination of "refractory anemia" in a more general proposal for reclassification of myeloid ...

    Research Article last updated 11/02/2016 - 9:37am.

  4. A phase 2 trial of high dose lenalidomide in patients with relapsed/refractory higher-risk myelodysplastic syndromes and acute myeloid leukaemia with trilineage dysplasia

    ... Limited therapies exist for patients with refractory and relapsed (RR) higher-risk myelodysplastic syndromes ...

    Research Article last updated 11/02/2016 - 9:17am.

  5. MEDALIST Trial

    ... (ECOG) score of 0, 1, or 2 5.    Subjects who ar refractory /intolerant/ineligible to prior ESA treatment, defined as: Refractory to prior Erythropoiesis- stimulating agents(ESA) treatment: ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  6. Types

    ... in bone marrow RA ( Refractory Anemia ) < 1 < 5 RARS (Refractory Anemia with Ring Sideroblasts < 1 ...

    Topic section last updated 11/14/2016 - 1:11pm.

  7. Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

    ... restricted to select patients. New strategies for ESA- refractory or relapsed patients include lenalidomide , alone or in ...

    Research Article last updated 12/09/2016 - 2:50pm.

  8. Left main crossover stenting in a patient with severe thrombocytopenia due to aplastic anemia

    ... 11 × 103/μL, hemoglobin 6.4 g/dL). Refractory heart failure persisted despite repeated conservative ...

    Research Article last updated 12/09/2016 - 2:08pm.

  9. REVERSE 1 INCB 18424-271

    ... With Corticosteroids for the Treatment of Steroid- Refractory Acute Graft-Versus-Host Disease - The purpose of this study is ... corticosteroids in subjects with Grades II to IV steroid-refractory acute graft-versus-host disease (GVHD) . ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  10. Eltrombopag for the treatment of aplastic anemia: current perspectives

    ... patients. A significant proportion of patients are refractory to IST or relapse after IST. Various strategies have been ... as an encouraging and promising agent for patients with refractory AA. It has demonstrated efficacy in restoring trilineage ...

    Research Article last updated 11/01/2016 - 2:01pm.