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  1. Moderate, Severe, and Very Severe Aplastic Anemia: How are treatment decisions made?

    ... but at this point it is only approved for patients with refractory aplastic anemia. This is when there is no response or success ... anemia returns. In our trials here at NIH, roughly half of refractory patients responded to eltrombopag. Now we have an option for those ...

    Interview last updated 10/14/2015 - 12:47pm.

  2. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... is indicated (e.g. hemophagocytic lymphohistiocytosis; refractory aplastic anemia or conjugated cytopenias; non-SCID ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  3. Share These Stories of Patients Fighting MDS

    ... research scientist has the MDS subtype known as RARS ( refractory anemia with ring sideroblasts). He struggled to come ...

    Page last updated 09/29/2014 - 11:49am.

  4. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... the World Health Organization (WHO) system as RA, RARS, refractory cytopenia with multilineage dysplasia (RCMD), RCMD and ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.

  5. Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

    ... AML in second or subsequent complete remission. MDS: refractory anemia with excess blasts (RAEB), or chronic ...

    Clinical Trial last updated 04/28/2016 - 2:08pm.

  6. Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

    ... recently completed a pilot study of eltrombopag in refractory SAA. We saw encouraging clinical results in a cohort of patients ...

    Clinical Trial last updated 04/25/2016 - 2:47pm.

  7. Acute Myeloid Leukemia (AML)

    ... present after the patient finishes standard therapy ( refractory leukemia):  There may be a different approach to treatment than ...

    Topic section last updated 07/07/2016 - 3:15pm.

  8. MDS: Diagnosis

    ... are more likely to become AML: * If you have RA ( Refractory Anemia) or RARS (Refractory Anemia with Ringed Sideroblasts), you have a 1 in 10 to 2 in 10 ...

    Page last updated 01/20/2015 - 4:42pm.

  9. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... stem cell transplantation (HSCT) or MM patients with refractory disease who may benefit from tandem autologous-nonmyeloablative ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  10. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... failed immunosuppressive therapy         3) Refractory anemia (RA) or RARS MDS patients who have associated transfusion ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.