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  1. Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

    ... Determine the incidence of relapse in patients with refractory anemia with excess blasts , refractory anemia with excess blasts in transformation, or acute myeloid ...

    Clinical Trial last updated 04/28/2016 - 8:49am.

  2. Drug: eltrombopag olamine Given PO Other Names: Promacta SB 497115 SB-497115 SB497115

    ... of GSK525762. Eligible subjects with relapsed refractory hematological malignancies will be enrolled in the OD and/or BID ... agent to be conducted in subjects with these relapsed and/or refractory hematological malignancies for which no standard therapies are ...

    Clinical Trial last updated 05/03/2016 - 12:03pm.

  3. Allo HSCT Using RIC for Hematological Diseases

    ... remission. Chronic Myelogenous Leukemia excluding refractory blast crisis: To be eligible in first chronic phase (CP1) ... of an additional dose of 200 cGy of TBI CML in refractory blast crisis Intermediate or high grade NHL, mantle cell ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  4. Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome

    ... that are commonly used to treat pediatric patients with refractory or relapsed acute myeloid leukemia (AML) ... and cytarabine in pediatric patients with relapsed or refractory AML or MDS. SECONDARY OBJECTIVES: Characterize the ...

    Clinical Trial last updated 04/29/2016 - 10:11am.

  5. Eltrombopag in aplastic anemia

    ... a potential therapy in case of stem cell depletion in refractory aplastic anemia. Eltrombopag was used for 43 aplastic anemia patients who were refractory to IST at National Institutes of Health (NIH), improving blood ...

    Research Review last updated 05/02/2016 - 9:13am.

  6. AML Therapy With Irradiated Allogeneic Cells

    ... Histologically proven non-M3 AML: Refractory /relapsed AML OR Initial diagnosis of AML in patient >= 60 ...

    Clinical Trial last updated 06/13/2016 - 3:14pm.

  7. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... confirmed are eligible Acute leukemia, primary refractory or beyond CR1 High risk acute myeloid leukemia in CR1 with ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  8. LY2606368 in Combination With Cytarabine and Fludarabine in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (HRMDS)

    ... drug combination when given to patients with relapsed or refractory AML or HRMDS will also be studied. ...

    Clinical Trial last updated 04/28/2016 - 1:47pm.

  9. Phase I Study of Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantation

    ... combination has been used in the treatment of relapsed/ refractory multiple myeloma and has been previously investigated in the ...

    Clinical Trial last updated 04/28/2016 - 10:20am.

  10. A Dose Escalation and Cohort Expansion Study of TEN-010 in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome

    ... pharmacokinetics of TEN-010 in patients with relapsed/ refractory acute myeloid leukemia (RR-AML) and hypomethylating agent ... cohorts of three or more patients with RR-AML or HMA-refractory MDS will be treated at escalating doses until a maximum tolerated ...

    Clinical Trial last updated 04/28/2016 - 10:02am.