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  1. Ramon V. Tiu, MD

    ... with aplastic anemia treated with ATG do not respond ( refractory aplastic anemia) and others have an initial response but lose it ... therapies for the treatment of patients with relapsed/refractory aplastic anemia. Alefacept is a novel immunosuppressive agent ...

    Grant Recipient last updated 10/30/2012 - 6:28pm.

  2. Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia.

    Journal Title:  Int J Hematol Primary Author:  Fu Y Author(s):  Fu Y, Wang Q,...

    Research Article last updated 11/26/2013 - 11:14am.

  3. Eltrombopag Added to IST Yields Encouraging Results

    ... responded to immunosuppressive therapy (IST). These refractory patients were continuing to require weekly transfusions for ...

    Interview last updated 05/24/2017 - 7:44am.

  4. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... Myelodysplastic syndrome of all subtypes including refractory anemia (RA) or all IPSS categories if severe ... Criteria (High risk patients on Arm 7) Patients with refractory leukemia or MDS may be taken to transplant in aplasia after ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  5. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... normal blood counts. Limitations of IST have included refractory disease, relapse and long-term risk of developing ... to excellent survival, the risk of events such as relapse, refractory disease, or clonal progression that we see with IST, was not seen ...

    Interview last updated 11/28/2016 - 2:58pm.

  6. Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

    ... Chronic myelogenous leukemia: all types except refractory blast crisis. Large-cell lymphoma, Hodgkin lymphoma and ... after initial therapy if chemotherapy sensitive. Refractory leukemia or MDS These patients may be taken to transplant in aplasia ...

    Clinical Trial last updated 06/06/2016 - 10:54am.

  7. Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant

    ... Chronic myelogenous leukemia: all types except refractory blast crisis. Chronic phase patients must have failed or been ... for debulking chemotherapy before transplant. Patients with refractory disease are eligible, unless has bulky disease and an estimated ...

    Clinical Trial last updated 05/02/2016 - 2:13pm.

  8. Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

    ... mutated patients 18 years of age or older with relapsed/ refractory AML (any number of relapses) including patients who may have ... of this study. Phase II FLT3-ITD mutated relapsed/refractory patients: Patients should have a diagnosis of AML ( de novo ...

    Clinical Trial last updated 05/23/2016 - 3:37pm.

  9. Extended Dosing With Eltrombopag for Severe Aplastic Anemia

    ... on continued cyclosporine administration. Patients with refractory severe cytopenias are at risk of dying from infection or ... which are expensive and inconvenient, Patients with refractory SAA are also at risk for progression to other hematologic disorders, ...

    Clinical Trial last updated 04/26/2016 - 9:36am.

  10. Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide

    ... a purine analog-containing regimen b. Relapsed, refractory , or progressive aggressive non Hodgkin's lymphoma (including ... acute lymphoblastic lymphoma must be in CR. c. Relapsed, refractory, or progressive Hodgkin's lymphoma meeting one of the following ...

    Clinical Trial last updated 05/02/2016 - 2:38pm.