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  1. A Biomarker-Directed Phase 2 Trial of SY-1425 in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

    ... the activity of SY-1425 in patients with relapsed/ refractory acute myeloid leukemia (AML) or high-risk myelodysplastic ...

    Clinical Trial last updated 08/24/2016 - 11:20am.

  2. Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide

    ... a purine analog-containing regimen b. Relapsed, refractory , or progressive aggressive non Hodgkin's lymphoma (including ... acute lymphoblastic lymphoma must be in CR. c. Relapsed, refractory, or progressive Hodgkin's lymphoma meeting one of the following ...

    Clinical Trial last updated 05/02/2016 - 2:38pm.

  3. Extended Dosing With Eltrombopag for Severe Aplastic Anemia

    ... on continued cyclosporine administration. Patients with refractory severe cytopenias are at risk of dying from infection or ... which are expensive and inconvenient, Patients with refractory SAA are also at risk for progression to other hematologic disorders, ...

    Clinical Trial last updated 04/26/2016 - 9:36am.

  4. Britta Will, PhD

    ... and improvements in overall survival, relapse and refractory disease continue to occur in some patients. Recent findings ...

    Grant Recipient last updated 07/07/2016 - 9:46am.

  5. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... with hematologic malignancies that have relapsed or are refractory after prior allogeneic transplant. Toxicity will be evaluated by ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  6. Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-3032b in Hematological Malignancies

    ... Recommended Phase II Dose (RP2D) in subjects with refractory or relapsed Acute Myelogenous Leukemia (AML), Acute ... blast phase, or high risk MDS in Part 1-Dose Escalation and refractory or relapsed AML or high risk Myelodysplastic Syndrome (MDS) in ...

    Clinical Trial last updated 04/29/2016 - 1:50pm.

  7. Drug: eltrombopag olamine Given PO Other Names: Promacta SB 497115 SB-497115 SB497115

    ... of GSK525762. Eligible subjects with relapsed refractory hematological malignancies will be enrolled in the OD and/or BID ... agent to be conducted in subjects with these relapsed and/or refractory hematological malignancies for which no standard therapies are ...

    Clinical Trial last updated 05/03/2016 - 12:03pm.

  8. Allo HSCT Using RIC for Hematological Diseases

    ... remission. Chronic Myelogenous Leukemia excluding refractory blast crisis: To be eligible in first chronic phase (CP1) ... of an additional dose of 200 cGy of TBI CML in refractory blast crisis Intermediate or high grade NHL, mantle cell ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  9. Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

    ... Determine the incidence of relapse in patients with refractory anemia with excess blasts , refractory anemia with excess blasts in transformation, or acute myeloid ...

    Clinical Trial last updated 04/28/2016 - 8:49am.

  10. Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome

    ... that are commonly used to treat pediatric patients with refractory or relapsed acute myeloid leukemia (AML) ... and cytarabine in pediatric patients with relapsed or refractory AML or MDS. SECONDARY OBJECTIVES: Characterize the ...

    Clinical Trial last updated 04/29/2016 - 10:11am.