Search | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. FDA approves new drug for relapsed or refractory AML

    ... approval to enasidenib for the treatment of relapsed or refractory AML Article Source:  ... for the treatment of adult patients with relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 (IDH2) ...

    Article last updated 08/30/2017 - 8:30am.

  2. Enasidenib in mutant-IDH2 relapsed or refractory acute myeloid leukemia

    ... in the largest patient subgroup, those with relapsed or refractory AML (n=176), from the phase 1 dose-escalation and expansion ... syndrome (IDH-DS; 7%). Among patients with relapsed or refractory AML, overall response rate was 40.3%, with median response duration ...

    Research Article last updated 06/08/2017 - 9:58am.

  3. Management of the refractory aplastic anemia patient: what are the options?

    ... 19, 2013 Refractory aplastic anemia (AA) is defined as lack of response to ... critical for AA patients, it is of paramount importance for refractory disease in view of the longer duration of pancytopenia and ...

    Research Article last updated 09/26/2013 - 3:05pm.

  4. Management of the refractory aplastic anemia patient: what are the options?

    ... 1, 2013 Refractory aplastic anemia (AA) is defined as a lack of response to ... critical for AA patients, it is of paramount importance for refractory disease in view of the longer duration of pancytopenia and ...

    Research Article last updated 01/07/2014 - 12:28pm.

  5. Non-myeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia

    ... approaches are urgently needed for patients with refractory severe aplastic anemia (SAA) who lack a matched sibling ... failed UD or cord blood transplant . Patients with refractory SAA are at risk of later clonal evolution to myelodysplastic ...

    Research Article last updated 08/04/2014 - 8:20am.

  6. Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia

    ... For patients with aplastic anemia (AA) who are refractory to anti-thymocyte globulin (ATG) and cyclosporine , a ... standard rabbit ATG and cyclosporine in nine patients with refractory or relapsed AA. RESULTS: After a median follow-up of 20 ...

    Research Article last updated 12/09/2015 - 1:27pm.

  7. Low efficacy and high mortality associated with clofarabine treatment of relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes

    ... nucleoside analog, has clinical activity in relapsed or refractory acute myelogenous leukemia (AML) and higher-risk ... for 84 patients treated with clofarabine for relapsed or refractory AML or MDS, either with clofarabine as monotherapy (n=19) or in ...

    Research Article last updated 03/02/2015 - 2:19pm.

  8. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... therapy (IST). The management of patients with refractory SAA after IST is a major challenge. Alternative donor BMT is best chance for cure in refractory SAA, but morbidity and mortality from graft failure and ... safely expand the donor pool in 16 consecutive patients with refractory SAA who did not have a matched sibling donor. Between July 2011 and ...

    Research Article last updated 01/24/2017 - 10:04am.

  9. Good riddance to the term "refractory anemia" in myelodysplastic syndromes

    ... 2016 The term " refractory anemia " was used in 1937 by Cornelius Parker Rhoads to ... the World Health Organization (WHO) proposed elimination of "refractory anemia" in a more general proposal for reclassification of myeloid ...

    Research Article last updated 11/02/2016 - 9:37am.

  10. A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

    ... Patients with relapsed/ refractory leukemias or advanced myelodysplastic syndrome (MDS) fare poorly ...

    Research Article last updated 06/28/2013 - 1:30pm.