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  1. Variations in erythropoiesis-stimulating agent administration in transfusion-dependent myelodysplastic syndromes impact response

    ... Erythropoiesis-stimulating agents (ESAs) reduce red blood cell (RBC) transfusions in approximately 40% of patients with ...

    Research Article last updated 05/26/2015 - 11:49am.

  2. Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

    ... Low endogenous erythropoietin levels and limited red blood cell transfusion history can predict response to ...

    Research Article last updated 08/04/2014 - 8:33am.

  3. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... on our trial went on successfully to have allogeneic stem cell transplantation. Are there any side effects? Very few. At ... National Institutes of Health, National Heart, Lung, and Blood Institute ...

    Interview last updated 07/06/2012 - 3:42pm.

  4. Debby Cook, Feeling at home in the muddy water

    ... when I was no longer neutropenic (low number of white blood cells), we were out for lunch and I saw a sign for a yoga studio.  I ... that I get to be his mom. Today I feel good.  My red blood cell counts, white blood cell counts and platelets are ...

    Patient Chronicle last updated 09/11/2017 - 8:30am.

  5. Personalized medicine for MDS

    ... patients into “lower-risk” disease, where improvement in blood counts is the main goal of therapy, and “higher-risk” disease, where ... 2 years.  -Lenalidomide works best in patients with red blood cell transfusion dependent MDS patients with lower-risk disease ...

    Research Review last updated 05/02/2016 - 9:44am.

  6. Patient Inspires Workplace Giving

    ... experienced what I now know as petechiae – little red dots all over my body caused by bleeding into the skin due to low ... other patients, we first knew something wasn’t right when blood work from a routine physical showed significantly low blood cell counts. ...

    Patient Chronicle last updated 06/28/2016 - 8:12am.

  7. Announcing AAMDSIF 2016 Research Awards

    ... set of clonal disorders characterized by ineffective blood cell development. These diseases are driven by many complex genetic and ... system. The result of this deficiency is a breakdown of red cells. If large quantities of red cells are destroyed, people become very ...

    Article last updated 06/09/2016 - 12:45pm.

  8. NHLBI profiles a member of the Foundation’s patient community.

    ... One Woman’s Determination Helped Her Defeat a Devastating Blood Disease Article Source:  ... the spongy tissue inside the bones — from making enough red blood cells, which carry oxygen to the different parts of the body; white ...

    Article last updated 06/13/2016 - 1:51pm.

  9. Can iron overload in patients with lower-risk myelodysplastic syndromes be reduced using erythropoiesis-stimulating agents?

    ... Erythropoiesis-stimulating agents (ESA) may reduce red blood cell transfusion requirements. MDS patients receiving ESA were ...

    Research Article last updated 12/09/2015 - 8:52am.

  10. Transfusion Thresholds, Quality of Life, and Current Approaches in Myelodysplastic Syndromes

    ... Hemoglobin thresholds and triggers for blood transfusions have changed over the years moving from a higher to a lower ... clinical trials are looking for a more liberal approach of red cell transfusion and the effect on quality of life as opposed to the ...

    Research Article last updated 06/23/2016 - 9:55am.