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  1. Eltrombopag now an approved therapy for certain patients with severe aplastic anemia

    ... Eltrombopag, works by helping to increase production of blood cells. According to Cynthia Dunbar, M.D., Head, Molecular ... of patients, the majority multi-lineage [ neutrophil , red cell, and platelets].  In some patients with normalized marrow function, ...

    Page last updated 08/27/2014 - 2:19pm.

  2. Research Retrospective for AA&MDSIF 30th Anniversary - Dr. Neal Young

    ... treating infections, especially fungal infections, excellent blood bank support means that platelets are readily available to most patients, changes in red blood cell transfusion methods have decreased the problem of ...

    Interview last updated 05/08/2013 - 2:51pm.

  3. Soliris

    ... the need for transfusions Reduce the breaking apart of red blood cells ( hemolysis ) over both the short and the long term ...

    Page last updated 06/29/2015 - 9:07am.

  4. MDS: Diagnosis

    ... To understand what is causing your symptoms and low blood counts, your doctor will take a detailed medical history. Your doctor may ... type in your blood sample. If the CBC shows a low number of red blood cells, white blood cells, or platelets, your doctor may look at the ...

    Page last updated 01/20/2015 - 4:42pm.

  5. PNH: Causes

    ... PIG-A. The abnormal stem cells turn into mature red blood cells that have mutant PIG-A. These are called PNH red blood cells. ...

    Page last updated 06/29/2015 - 8:44am.

  6. MDS—The Past 40 Years. A Look at the Emerging Awareness and Classification of Myelodysplastic Syndromes.

    ... century. Based on the percentage of blasts (young, immature blood cells) in bone marrow and blood, the FAB system had five MDS ... blood cell counts of any or all three types of blood cells (red blood cells, white blood cells, or platelets). From these combined ...

    Page last updated 10/19/2015 - 2:29pm.

  7. North American Pediatric Aplastic Anemia Consortium Symposium

    ... adults that causes the bone marrow to stop making blood cells.  As with all rare diseases, there is a relative lack of research ... been reported to show mild dysplasia and patchy areas of red blood cell , or erythroid, precursors. However, in the absence of an MDS ...

    Page last updated 10/31/2013 - 4:06pm.

  8. Overlap Syndromes: When PNH Appears with Aplastic Anemia

    ... for different reasons. In classic PNH, there is breakdown of red cells and the reticulocyte count is high, but with aplastic anemia, ... eculizumab (Soliris®) or anticoagulants to prevent blood clots. Aplastic anemia patients need immunosuppression, generally being ...

    Interview last updated 04/15/2015 - 9:39am.

  9. ASH 2012 - Reviewing MDS Progress from Research and Clinical Perspectives

    ... (Procrit®) or darbepoetin (Aranesp®) work for low red blood cell counts. Romiplostin can be considered a platelet growth ...

    Interview last updated 02/07/2013 - 1:28pm.

  10. Lower-Risk MDS: Diagnosis and Treatment Options

    ... or higher-risk. The first criterion is the number of low blood counts, specifically defined as hemoglobin level less than 10 ... transfusion-independent, if they have been needing red blood cell transfusions. Lenalidomide is a pill that is usually taken ...

    Interview last updated 05/18/2012 - 1:28pm.