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  1. Overlap Syndromes: When PNH Appears with Aplastic Anemia or MDS

    ... (scarring in the marrow), a chronically high white blood cell or platelet count, especially if they have the JAK2 ... for different reasons. In classic PNH, there is breakdown of red cells and the reticulocyte count is high, but with aplastic anemia, ...

    Interview last updated 05/14/2015 - 1:53pm.

  2. Bone Marrow and Stem Cell Transplantation

    ... in our Online Learning Center . What are blood-forming stem cells? Blood cells are made in your bone marrow, a ... of themselves and produce all three types of blood cells – red blood cells, white blood cells and platelets. When blood cells are mature ...

    Page last updated 09/30/2014 - 11:47am.

  3. Eltrombopag: Recent Discoveries on Potential New Applications for Aplastic Anemia

    ... in the Hematology Branch of the National Heart, Lung, and Blood Institute (NHLBI) at the Clinical Center of the National Institutes of ... counts in some patients, but also improve white and red blood cell counts. This was a surprising finding, as the drug was ...

    Interview last updated 02/14/2014 - 2:01pm.

  4. Research Retrospective for AA&MDSIF 30th Anniversary - Dr. Neal Young

    ... treating infections, especially fungal infections, excellent blood bank support means that platelets are readily available to most patients, changes in red blood cell transfusion methods have decreased the problem of ...

    Interview last updated 05/08/2013 - 2:51pm.

  5. Eltrombopag now an approved therapy for certain patients with severe aplastic anemia

    ... Eltrombopag, works by helping to increase production of blood cells. According to Cynthia Dunbar, M.D., Head, Molecular ... of patients, the majority multi-lineage [ neutrophil , red cell, and platelets].  In some patients with normalized marrow function, ...

    Page last updated 08/27/2014 - 2:19pm.

  6. MDS: Diagnosis

    ... To understand what is causing your symptoms and low blood counts, your doctor will take a detailed medical history. Your doctor may ... type in your blood sample. If the CBC shows a low number of red blood cells, white blood cells, or platelets, your doctor may look at the ...

    Page last updated 01/20/2015 - 4:42pm.

  7. North American Pediatric Aplastic Anemia Consortium Symposium

    ... adults that causes the bone marrow to stop making blood cells.  As with all rare diseases, there is a relative lack of research ... been reported to show mild dysplasia and patchy areas of red blood cell , or erythroid, precursors. However, in the absence of an MDS ...

    Page last updated 10/31/2013 - 4:06pm.

  8. Soliris

    ... the need for transfusions Reduce the breaking apart of red blood cells ( hemolysis ) over both the short and the long term ...

    Page last updated 06/29/2015 - 9:07am.

  9. PNH: Causes

    ... PIG-A. The abnormal stem cells turn into mature red blood cells that have mutant PIG-A. These are called PNH red blood cells. ...

    Page last updated 06/29/2015 - 8:44am.

  10. ASH 2012 - Reviewing MDS Progress from Research and Clinical Perspectives

    ... (Procrit®) or darbepoetin (Aranesp®) work for low red blood cell counts. Romiplostin can be considered a platelet growth ...

    Interview last updated 02/07/2013 - 1:28pm.