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  1. Acute Myeloid Leukemia (AML)

    ... Acute myeloid leukemia (AML) is a blood cancer. It happens when young abnormal white blood cells called ... copies of themselves quickly. This slows the production of red blood cells and platelets, causing tiredness from anemia and a risk ...

    Topic section last updated 07/07/2016 - 3:15pm.

  2. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... and radiation at reduced doses followed by a cord blood transplant are at treating cancer. The stem cells chosen for the ... score with life threatening cytopenia (s), including red cell or platelet transfusion dependence. Receipt of at least ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  3. Chronic Lymphocytic Leukemia (CLL)

    ... (CLL) is a type of cancer that involves certain white blood cells (lymphocytes) that develop in the bone marrow and lymph ... cells, which can cause the marrow to produce fewer red cells, white cells and platelets with these results: A low number of ...

    Topic section last updated 07/07/2016 - 3:18pm.

  4. More is better: Combination therapies for myelodysplastic syndromes

    ... characterized by ineffective maturation of cells, low blood counts, and risk of transformation to acute myeloid leukemia (AML).  ... alpha in lower-risk MDS patients in an effort to reduce red blood cell transfusion dependence. -The current FDA approved agents ...

    Research Review last updated 05/02/2016 - 9:14am.

  5. Epoetin Alfa

    ... Epoetin alfa can help improve red blood cell counts in bone marrow failure disease patients whose ...

    Drug last updated 03/24/2016 - 12:32pm.

  6. Darbepoetin Alfa

    ... agents (ESAs). Darbepoetin alfa can help improve red blood cell counts in bone marrow failure patients whose natural ...

    Drug last updated 03/24/2016 - 12:32pm.

  7. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... recover faster following a stem cell transplant . Blood stem cells are very young blood cells that grow in the body to become red or white blood cells or platelets. The transplant uses stem cells in the ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  8. Incidence and Burden of the Myelodysplastic Syndromes

    ... where cells are not maturing properly resulting in low blood counts, increasing the risk of infection, bleeding, and fatigue.  It is ... Medicare costs and require more hospital services.  -Red-blood cell transfusion dependence is associated with increased mortality ...

    Research Review last updated 05/02/2016 - 9:11am.

  9. Heather Putney’s Trials (and Travels) with Aplastic Anemia

    ... to the gynecologist and a painless bruise led to a complete blood count draw, which showed markedly low platelets and hematocrit . ... Within two months, I was transfusion dependent for both red blood cells and platelets. In June, I was admitted for an allogenic bone ...

    Patient Chronicle last updated 08/15/2016 - 8:42am.

  10. Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    ... undergoing unrelated donor peripheral blood stem cell transplant . Giving chemotherapy and total-body ... may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted ...

    Clinical Trial last updated 04/28/2016 - 1:49pm.