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  1. More is better: Combination therapies for myelodysplastic syndromes

    ... characterized by ineffective maturation of cells, low blood counts, and risk of transformation to acute myeloid leukemia (AML).  ... alpha in lower-risk MDS patients in an effort to reduce red blood cell transfusion dependence. -The current FDA approved ...

    Research Review last updated 05/02/2016 - 9:14am.

  2. Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

    ... The are a variety of cancerous diseases of the blood and bone marrow that can be potentially cured by bone marrow ... . The stem cells help to build new functioning bone marrow, red cells, white cells, and platelets. In addition, the immune cells from the ...

    Clinical Trial last updated 04/28/2016 - 2:08pm.

  3. FAQs

    ... anemia happens when your bone marrow stops making enough blood-forming stem cells . Most experts believe aplastic anemia occurs ... ) is a rare and serous blood disease that causes your red blood cells to break apart. PNH occurs because of a genetic change to some ...

    Topic section last updated 03/02/2016 - 11:42am.

  4. Extended Dosing With Eltrombopag for Severe Aplastic Anemia

    ... Severe aplastic anemia (SAA) is a life-threatening blood disease that can be successfully treated with immunosuppressive drug ... and they require regular platelet and/or red blood cell transfusions, which are expensive and inconvenient, Patients ...

    Clinical Trial last updated 04/26/2016 - 9:36am.

  5. Safety and Effect of GL-ONC1 Administered IV With or Without Eculizumab Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery

    ... ); Hemoglobin ≥ 9.0 g/dL(with or without red blood cell (RBC) transfusion); Serum creatinine ≤ 1.5 × upper limit ...

    Clinical Trial last updated 04/28/2016 - 1:57pm.

  6. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... dependence* ANC <1000 x 109/L Hgb <8 gm/dl or red cell transfusion dependence* Myelodysplastic Syndrome (MDS) ... filgrastim neupogen Biological: Peripheral blood stem cell The source of stem cells for all patients will be ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  7. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... recover faster following a stem cell transplant . Blood stem cells are very young blood cells that grow in the body to become red or white blood cells or platelets. The transplant uses stem cells in the ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  8. Transplantation Basics

    ... are gathered from either bone marrow , umbilical cord blood, and peripheral blood of a suitable donor and are placed in an MDS ... replacing mature blood cells to treat anemia (from low red blood cell counts) or to increase the platelet count. “Blood ...

    Interview last updated 04/05/2013 - 2:33pm.

  9. Heather Putney’s Trials (and Travels) with Aplastic Anemia

    ... to the gynecologist and a painless bruise led to a complete blood count draw, which showed markedly low platelets and hematocrit . ... Within two months, I was transfusion dependent for both red blood cells and platelets. In June, I was admitted for an allogenic bone ...

    Patient Chronicle last updated 08/15/2016 - 8:42am.

  10. Medical Resources

    ... an expert to find an answer. Blood and Transplant Information Understanding your ... & cellular therapies worldwide. American Red Cross (800) 733-2767 Asians for Miracle Marrow ...

    Page last updated 08/20/2015 - 8:34am.